|1.||Liu, Xin: 1 article (01/2015)|
|2.||Zhao, Jingxia: 1 article (01/2015)|
|3.||Maheshwari, Dinesh Kumar: 1 article (01/2015)|
|4.||Liu, Ying: 1 article (01/2015)|
|5.||Chhaya, Gadgoli: 1 article (01/2015)|
|6.||Singh, Lokesh Kumar: 1 article (01/2015)|
|7.||Lin, Yan: 1 article (01/2015)|
|8.||Di, Tingting: 1 article (01/2015)|
|9.||Shukla, Shruti: 1 article (01/2015)|
|10.||Wang, Yan: 1 article (01/2015)|
|1.||Psoriasis (Pustulosis Palmaris et Plantaris)
01/01/2015 - "Mice treated with alkannin at varying concentration showed obvious remission in psoriasis-like skin lesion compared to control group, with decreased PASI score, obviously reduced vertical thickness of epidermis. "
01/01/2015 - "To investigate the effect of β, β-dimethylacryloyl alkannin, a main component of Lithospermum erythrorhizon, on activated dendritic cells (DCs) in a psoriasis mouse model. "
01/01/2015 - "β, β-dimethylacryloyl alkannin could suppress the function of activated DCs in imiquimod-induced psoriasis mouse model."
01/01/2015 - "BALB/c mice were used to establish the animal model for psoriasis-like skin lesion; alkannin at 10 mg/kg (high), 5 mg/kg (medium), 2.5 mg/kg (low), respectively, were intragastrically administered. "
01/01/2015 - "Suppressive effect of β, β-dimethylacryloyl alkannin on activated dendritic cells in an imiquimod-induced psoriasis mouse model."
|2.||Urinary Tract Infections (Urinary Tract Infection)
01/01/2015 - "Antibacterial effect of butyryl alkannin from Arnebia euchroma against vancomycin-resistant pathogens of Enterococcus faecalis causing urinary tract infections."
01/01/2015 - "This study was carried out to investigate the biomedicinal potential of a bioactive marker component, butyryl alkannin, isolated from n-hexane root extract of Arnebia euchroma against various vancomycin-resistant Enterococcus (VRE) isolates of Enterococcus faecalis causing urinary tract infections. "
01/01/2015 - "This study aims to explore the effect of alkannin on the growth and invasion of glioma cells and its mechanism. "
01/01/2015 - "Alkannin can inhibit the growth and invasion of glioma cells C6 through IQGAP/mTOR signal pathway."
01/01/2015 - "Alkannin (1 μM, 3 μM and 10 μM) can significantly inhibit the growth, proliferation, migration and invasion of glioma cells C6 with dose dependent. "
01/01/2015 - "The effects of alkannin on the growth and invasion of glioma cells were detected with MTT assay, clone forming test and transwell assay. "
01/01/2015 - "Alkannin inhibits growth and invasion of glioma cells C6 through IQGAP/mTOR signal pathway."
09/01/2014 - "Their cytotoxicities against three kinds of tumor cells and a normal cell line were tested and compared with alkannin and shikonin. "
10/20/2011 - "As PKM2 universally expresses in cancer cells and dictates the last rate-limiting step of glycolysis vital for cancer cell proliferation and survival, enantiomeric shikonin and alkannin may have potential in future clinical application."
07/01/2010 - "SYUNZ-16, a newly synthesized alkannin derivative, induces tumor cells apoptosis and suppresses tumor growth through inhibition of PKB/AKT kinase activity and blockade of AKT/FOXO signal pathway."
10/20/2011 - "Shikonin and alkannin significantly inhibited the glycolytic rate, as manifested by cellular lactate production and glucose consumption in drug-sensitive and resistant cancer cell lines (MCF-7, MCF-7/Adr, MCF-7/Bcl-2, MCF-7/Bcl-x(L) and A549) that primarily express PKM2. "
10/20/2011 - "Here, we showed that shikonin and its analogs are inhibitors of tumor-specific pyruvate kinase-M2 (PKM2), among which shikonin and its enantiomeric isomer alkannin were the most potent and showed promising selectivity, that is, shikonin and alkannin at concentrations that resulted in over 50% inhibition of PKM2 activity did not inhibit PKM1 and pyruvate kinase-L (PKL). "
|5.||Colorectal Neoplasms (Colorectal Cancer)
|5.||Pyruvic Acid (Pyruvate)