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tyrosine betaine

from Ephedra roots

Also Known As:

maokonine; (S)-alpha-carboxy-4-hydroxy-N,N,N-trimethylbenzeneethanaminium, hydroxide, inner salt

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Tyrosine: 10509
        tyrosine betaine: 1

Experts

1.	Braga, Gilberto Ubida Leite: 1 article (01/2018)
2.	Carmona, Adriana Karaoglanovic: 1 article (01/2018)
3.	Carvalho, Ivone: 1 article (01/2018)
4.	Kawano, Daniel Fabio: 1 article (01/2018)
5.	Machado, Mauricio Ferreira Marcondes: 1 article (01/2018)
6.	de Carvalho, Marcelo Rodrigues: 1 article (01/2018)

Related Diseases

1.	Heart Failure 01/01/2018 - "Biological and In silico Studies on Synthetic Analogues of Tyrosine Betaine as Inhibitors of Neprilysin - A Drug Target for the Treatment of Heart Failure." 01/01/2018 - "Because of the structural similarity with other inhibitors of neprilysin (NEP), an enzyme explored for the treatment of heart failure, we devised the synthesis of tyrosine betaine and three analogues to be subjected to in vitro NEP inhibition assays and to molecular modeling studies. "
2.	Alzheimer Disease (Alzheimer's Disease) 01/01/2018 - "Tyrosine betaine remains as a starting point for the development of NEP inhibitors because of the low probability of BBB permeation and, consequently, of NEP inhibition at the Central Nervous System, which is associated to an increment in the Aβ levels and, accordingly, with a higher risk for the onset of Alzheimer's disease."

Related Drugs and Biologics

1.	Neprilysin (Neutral Endopeptidase)
2.	Enzymes