phenazepam

RN given refers to parent cpd

Also Known As:

7-bromo-5-(2-chlorophenyl) 1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-bromo-5-(2-chlorphenyl)-1,2-dihydro-3H-1,4-benzodiazepin-2-one; fenazepam; phenazepam, 2-(14)C-labeled cpd

Networked: 59 relevant articles (9 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzazepines: 5
      - Benzodiazepines: 8452
        phenazepam: 59

Experts

1.	Neznamov, G G: 5 articles (01/2020 - 03/2009)
2.	Dorofeeva, O A: 3 articles (01/2020 - 03/2009)
3.	Siuniakov, S A: 3 articles (01/2012 - 03/2009)
4.	Grishina, Elena A: 2 articles (01/2020 - 12/2018)
5.	Savchenko, Ludmila M: 2 articles (01/2020 - 12/2018)
6.	Sychev, Dmitry A: 2 articles (01/2020 - 12/2018)
7.	Zastrozhin, Michael S: 2 articles (01/2020 - 12/2018)
8.	Bochkarev, V K: 2 articles (01/2018 - 01/2012)
9.	Chobanu, I K: 2 articles (01/2015 - 01/2014)
10.	Kost, N V: 2 articles (01/2015 - 01/2014)

Related Diseases

1.	Adjustment Disorders (Adjustment Disorder) 01/01/2019 - "Randomized controlled studies have demonstrated its anxiolytic efficacy in patients with adjustment disorders (ADs) with anxiety, showing it to be superior to buspirone and comparable to lorazepam and phenazepam, with a greater number of markedly improved responders and a better therapeutic index. "
2.	Seizures (Absence Seizure) 09/01/1982 - "Phenazepam (1.4 mg/kg) abolished seizures and in a dose of 0.1-0.7 mg/kg protected the animals from death and considerably relieved seizure manifestations. " 07/10/2012 - "There were 26 seizures of phenazepam by the Police in the time period studied, some of the batches consisted of a mixture of phenazepam and stimulant designer drugs. " 08/01/1983 - "The effects of trifluoperazine and haloperidol on protective activity of phenazepam were studied during seizures in mice treated with pentylenetetrazole (an index used for the appraisal of tranquilizing activity) as was their action on the phenazepam-induced depression of the test potential in the recovery cycles of somatosensory primary response. " 04/01/1981 - "The combined use of di-n-propylacetate with phenazepam, diazepam, phenobarbital or phenytoin was shown to be followed by reciprocal potentiation of the anticonvulsant activity of the drugs in a variety of experimental epileptic seizures in mice according to the tests of shock and antagonism with corasole and thiosemicarbazide. "
3.	Somatoform Disorders (Somatoform Disorder) 01/01/2016 - "To assess the efficacy of monotherapy with sertraline or its combinations with phenazepam or thioridazine in patients with somatoform disorders. " 01/01/2015 - "Authors explored the anxiolytic effect and tolerability of monotherapy with phenazepam (30 patients) and complex treatment with selank and phenazepam (40 patients) in anxiety-phobic, hypochondriac and somatoform disorders (ICD-10 items F40.2-9, F41.1-9, F45.0-2). " 01/01/2014 - "A comparative study of the anxiolytic effect and tolerability of selank and phenazepam was carried out in 60 patients with phobic-anxiety- and somatoform disorders (F40.2-9, F41.1-9, F45.0-1 by ICD-10) were examined. "
4.	Neurotic Disorders (Neuroses) 01/01/1986 - "Interaction between the clinical, EEG-effects and phenazepam concentration in the blood was studied in 111 patients with neurotic disorders after intake of the test drug dose (2 mg) administered singly and on the 14th day of the treatment. " 01/01/1989 - "Combined therapy of neurotic disorders is most effective with tranquilizers (phenazepam, nitrazepam, radedorm or éunoktin)."
5.	Mental Disorders (Mental Disorder) 07/01/1997 - "[The therapeutic efficacy and the effect of gidazepam and fenazepam on the psychophysiological status and on the performance of operators with mental disorders at a neurotic level]." 01/01/2005 - "Using combined psychopharmacotherapy (sonapax, neuleptil, haloperidol, coaxil, cipramil, phenazepam, xanax, mexidol, nootropil, etc) and an adequate psychotherapy basing on the principle of simultaneous biological and social action on poststroke patients (or persons socially significant for them and unit personnel), it was possible to raise quality of neurological as well as psychopharmacological and psychotherapeutic, in case of comorbid mental disorders, care that proved to be a main factor of early inpatient stage of psychosocial rehabilitation. "

Related Drugs and Biologics

1.	Anti-Anxiety Agents (Anxiolytics)
2.	Diazepam (Valium)
3.	Lorazepam (Ativan)
4.	Buspirone (Buspar)
5.	Sertraline (Zoloft)
6.	Thioridazine (Mellaril)
7.	Clonazepam (Rivotril)
8.	Scopolamine (Hyoscine)
9.	GABA-A Receptors (GABA(A) Receptor)
10.	Nitrazepam (Serenade)

Related Therapies and Procedures

1.	Therapeutics
2.	Intraperitoneal Injections
3.	Oral Administration