|1.||Ryan, Anderson J: 3 articles (11/2007 - 03/2004)|
|2.||Gould, Sarah: 2 articles (11/2007 - 07/2004)|
|3.||Jamin, Y: 1 article (04/2014)|
|4.||Boult, J K R: 1 article (04/2014)|
|5.||Robinson, S P: 1 article (04/2014)|
|6.||Waterton, J C: 1 article (04/2014)|
|7.||Ulloa, J: 1 article (04/2014)|
|8.||Li, J: 1 article (04/2014)|
|9.||Cummings, C: 1 article (04/2014)|
|10.||Sinkus, R: 1 article (04/2014)|
|1.||Colorectal Neoplasms (Colorectal Cancer)
04/02/2014 - "In this study, MRE was used to quantify (kPa) the absolute value of the complex shear modulus |G*|, elasticity Gd and viscosity Gl of SW620 human colorectal cancer xenografts before and 24 h after treatment with either 200 mg kg(-1) of the vascular disrupting agent ZD6126 (N-acetylcolchinol-O-phosphate) or vehicle control, and the data were compared with changes in water diffusivity measured by diffusion-weighted magnetic resonance imaging. "
01/01/2007 - "All analogues were evaluated as antimicrotubule agents and against a panel of cancer-cell lines using colchicine (1) and N-acetylcolchinol (3) as references. "
07/01/2004 - "The vascular targeting agent ZD6126 is a water-soluble prodrug of N-acetylcolchinol that acts by disrupting the cytoskeleton of tumor endothelial cells. "
04/01/2005 - "We have previously reported that in vitro N-acetylcolchinol disrupts microtubules and induces rapid changes in endothelial cell morphology, which in a tumor would lead to a rapid loss of tumor vessel integrity and subsequent extensive tumor necrosis. "
03/01/2004 - "Single dose of the antivascular agent, ZD6126 (N-acetylcolchinol-O-phosphate), reduces perfusion for at least 96 hours in the GH3 prolactinoma rat tumor model."
|3.||Myocardial Ischemia (Ischemic Heart Diseases)
11/21/2007 - "Antivascular agents that act by destabilizing microtubules, such as ZD6126 (N-acetylcolchinol-O-phosphate), are associated with adverse cardiovascular effects, including transient hypertension, cardiac ischemia, myocardial infarction, and increases in circulating levels of markers of cardiac damage (e.g., troponins). "
|3.||glucuronyl glucosamine glycan sulfate (Vessel)
|1.||Heterologous Transplantation (Xenotransplantation)