HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

stearoyl-coenzyme A (stearoyl-CoA)

Also Known As:
stearoyl-CoA; coenzyme A, stearoyl-; stearyl-CoA
Networked: 80 relevant articles (2 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ntambi, James M: 13 articles (03/2014 - 07/2002)
2. Miyazaki, Makoto: 6 articles (01/2010 - 07/2002)
3. Flowers, Matthew T: 6 articles (01/2010 - 06/2006)
4. Liu, Xueqing: 4 articles (01/2010 - 06/2006)
5. Chu, Kiki: 4 articles (01/2010 - 09/2006)
6. Sampath, Harini: 4 articles (01/2010 - 12/2005)
7. Polotsky, Vsevolod Y: 3 articles (04/2010 - 06/2007)
8. Wang, Hui: 2 articles (07/2015 - 04/2013)
9. Vessby, Bengt: 2 articles (03/2014 - 07/2007)
10. Igal, R Ariel: 2 articles (09/2012 - 06/2011)

Related Diseases

1. Obesity
2. Insulin Resistance
3. Neoplasms (Cancer)
4. Dyslipidemias (Dyslipidemia)
06/01/2006 - "Previous studies using stearoyl-CoA desaturase-1-deficient (SCD1-deficient) mice have shown that this enzyme plays an important role in many diseases of altered cellular metabolism including obesity, insulin resistance, and dyslipidemia. "
11/07/2008 - "Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase."
03/01/2014 - "Although a clear causal relationship of OSA and dyslipidemia is yet to be demonstrated, there is increasing evidence that chronic intermittent hypoxia, a major component of OSA, is independently associated and possibly the root cause of the dyslipidemia via the generation of stearoyl-coenzyme A desaturase-1 and reactive oxygen species, peroxidation of lipids, and sympathetic system dysfunction. "
11/07/2008 - "We have previously shown that C57BL/6J mice exposed to CIH and a high-cholesterol diet develop dyslipidemia, atherosclerosis of the aorta, and upregulation of a hepatic enzyme of lipoprotein secretion, stearoyl coenzyme A desaturase 1 (SCD-1). "
06/15/2007 - "Compared with mice exposed to intermittent air and a high-cholesterol diet, combined exposure to CIH and a high-cholesterol diet resulted in marked progression of dyslipidemia with further increases in serum total cholesterol and low-density lipoprotein cholesterol (124 +/- 4 vs. 106 +/- 6 mg/dl; p < 0.05), a twofold increase in serum lipid peroxidation, and up-regulation of an important hepatic enzyme of lipoprotein secretion, stearoyl-coenzyme A desaturase-1. "
5. Hyperlipidemias (Hyperlipidemia)

Related Drugs and Biologics

1. Fatty Acid Synthetase Complex (Fatty Acid Synthase)
2. Acetyl-CoA Carboxylase
3. Biological Markers (Surrogate Marker)
4. palmitoleic acid
5. Monounsaturated Fatty Acids
6. Fatty Acids (Saturated Fatty Acids)
7. Linoleic Acid (Linoleate)
8. alpha-Linolenic Acid (Linolenic Acid)
9. Glucose (Dextrose)
10. tallow

Related Therapies and Procedures

1. Aftercare (After-Treatment)