|1.||Chen, Jyh-Yih: 8 articles (02/2015 - 01/2011)|
|2.||Huang, Tsui-Chin: 4 articles (04/2014 - 01/2011)|
|3.||Pan, Chieh-Yu: 3 articles (02/2015 - 12/2013)|
|4.||Wu, Chang-Jer: 3 articles (04/2014 - 12/2013)|
|5.||Huang, Han-Ning: 3 articles (04/2014 - 12/2013)|
|6.||Chan, Yi-Lin: 2 articles (01/2014 - 12/2013)|
|7.||Yu, Chao Yuan: 1 article (02/2015)|
|8.||Chiou, Ming-Tang: 1 article (02/2015)|
|9.||Lin, Chao-Nan: 1 article (02/2015)|
|10.||Chien, Chi-Hsien: 1 article (02/2015)|
08/01/2012 - "Overall, these results indicate that pardaxin has the potential to be a novel therapeutic agent to treat fibrosarcomas."
08/01/2012 - "The antitumor activity of pardaxin, a fish antimicrobial peptide, has not been previously examined in in vitro and in vivo systems for treating murine fibrosarcoma. "
08/01/2012 - "Pardaxin, a fish antimicrobial peptide, exhibits antitumor activity toward murine fibrosarcoma in vitro and in vivo."
02/10/2015 - "We previously demonstrated that pardaxin has anti-tumor activity against murine fibrosarcoma, both in vitro and in vivo. "
01/01/2011 - "In the present study, we examined the antitumor activity of pardaxin against human fibrosarcoma HT-1080 cells; pardaxin inhibited cell proliferation by inducing apoptosis, as demonstrated by an increase in the externalization of plasma membrane phosphatidylserine and the presence of chromatin condensation. "
02/10/2015 - "Local injection of pardaxin resulted in a significant reduction of perianal gland adenoma growth between 28 and 38 days post-treatment. "
02/10/2015 - "Our findings indicate that pardaxin has strong therapeutic potential for treating perianal gland adenomas in dogs. "
02/10/2015 - "The antimicrobial peptide pardaxin exerts potent anti-tumor activity against canine perianal gland adenoma."
02/10/2015 - "In this study, we examined the anti-tumor activity, toxicity profile, and maximally-tolerated dose of pardaxin treatment in dogs with different types of refractory tumor. "
04/01/2014 - "Previous studies have shown that pardaxin selectively triggers the death of cancer cells, initiating the development of a pardaxin-based cancer vaccine; however, the underlying mechanism by which pardaxin kills cancer cells has not yet been elucidated. "
08/01/2012 - "In this study, the antitumor activity of synthetic pardaxin was tested using murine MN-11 tumor cells as the study model. "
04/01/2014 - "Importantly, pardaxin treatment or c-FOS overexpression induced cell death in diverse cancer cell lines, indicating that pardaxin and c-FOS may possess therapeutic potential for use in cancer treatment."
12/01/2013 - "A cancer vaccine based on the marine antimicrobial peptide pardaxin (GE33) for control of bladder-associated tumors."
|4.||Wounds and Injuries (Trauma)
01/01/2014 - "In this study, we investigated whether pardaxin promoted healing of contaminated wounds in mice. "
01/01/2014 - "Pardaxin decreased MRSA bacterial counts in the wounded region and also enhanced wound closure. "
01/01/2014 - "Use of the antimicrobial peptide pardaxin (GE33) to protect against methicillin-resistant Staphylococcus aureus infection in mice with skin injuries."
|5.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/01/2015 - "In Vitro and in Vivo Anticancer Activity of Pardaxin against Proliferation and Growth of Oral Squamous Cell Carcinoma."
01/01/2015 - "The present study investigated the anticancer activity of pardaxin in oral squamous cell carcinoma (OSCC) cells in the hamster buccal pouch model with or without 7,12-dimethylbenz[a]anthracene (DMBA) pretreatment. "
|9.||Polyglutamic Acid (Polyglutamate)
|2.||Heterologous Transplantation (Xenotransplantation)