oxitropium (oxitropium bromide)

RN given refers to bromide; structure

Also Known As:

oxitropium bromide; (8r)-6 beta,7 beta-epoxy-8-ethyl-3 alpha((-)-tropoyl)-1 alpha H, 5 alpha H-tropanium bromide; Ba 253; Ba 253Br; Ba-253; Ba-253Br; Oxivent; Tersigat; Ventilat; oxitropium iodide, (R)-isomer; oxitropium iodide, (S)-isomer; oxytropium bromide

Networked: 78 relevant articles (13 outcomes, 20 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Arimura, Kimiyoshi: 3 articles (01/2008 - 05/2006)
2.	Higashimoto, Ikkou: 3 articles (01/2008 - 05/2006)
3.	Matsuyama, Wataru: 3 articles (01/2008 - 05/2006)
4.	Osame, Mitsuhiro: 3 articles (01/2008 - 05/2006)
5.	Koreeda, Yoshimizu: 2 articles (01/2008 - 01/2007)
6.	Mitsuyama, Hideo: 2 articles (01/2008 - 01/2007)
7.	Boveri, B: 2 articles (01/2003 - 03/2002)
8.	Carlucci, P: 2 articles (01/2003 - 03/2002)
9.	Casanova, F: 2 articles (01/2003 - 03/2002)
10.	Cazzola, M: 2 articles (01/2003 - 03/2002)

Related Diseases

1.	Chronic Obstructive Pulmonary Disease (COPD) 01/01/2002 - "An initial search was carried out using the Cochrane Airways Group COPD RCT register using the search terms: (nasal ventilat* OR positive pressure OR NIPPV). " 07/01/2001 - "We examined the pulmonary function, static respiratory pressures, and ventilation during exercise, before and after inhalation of oxitropium bromide (OTB) in 12 male patients with COPD (mean age 82.1 +/- 0.6 years). " 06/01/2000 - "The effects of oxitropium bromide on exercise performance in patients with stable chronic obstructive pulmonary disease. " 11/01/1997 - "We examined pulmonary function, static respiratory pressure, and dyspneic sensations during exercise before and after the inhalation of oxitropium bromide (OTB) in 14 male patients with COPD. " 01/01/1995 - "Depending upon the balance between efficacy and side effects, oxitropium bromide may be preferred in the treatment of patients with COPD."
2.	Asthma (Bronchial Asthma) 10/01/1986 - "Eighteen patients (aged 18 to 76 years; seven men) with documented nocturnal asthma were studied in a double-blind randomized cross-over study in which they received either oxitropium bromide (200 micrograms or 400 micrograms) or placebo in a single dose at night for two-week periods. " 01/01/1984 - "Treatment of adult asthma: controlled double-blind clinical trial of oxitropium bromide." 01/01/1989 - "Effect of four-week treatment with oxitropium bromide on lung mucociliary clearance in patients with chronic bronchitis or asthma." 01/01/1989 - "Oxitropium bromide (OXBR) is a new anticholinergic drug, which is expected to be useful in the treatment of nocturnal asthma. " 10/01/1997 - "We studied 12 patients with asthma in a prospective, randomised, single-blind, single-dummy, three-period crossover trial comparing placebo (2 puffs t.d.s.), salbutamol (200 micrograms t.d.s.) and oxitropium bromide (200 micrograms t.d.s.) for 28 days each. "
3.	Infections 04/01/2004 - "The mean (SD) increase in FEV(1) after oxitropium bromide administration was significantly greater in patients with active HCV (95 [7] mL) than in HCV-negative asthmatic patients (68 [12] mL) and asthmatic patients with inactive HCV infection (69 [6] mL; p < 0.001). " 04/01/2004 - "Increased responses to inhaled oxitropium bromide in asthmatic patients with active hepatitis C virus infection." 02/01/1994 - "The mean PEFR showed a statistically significant fall in morning values during the early stages of infection which lessened with recovery but no effect of treatment with oxitropium bromide was observed (P > 0.05). " 04/01/2004 - "In patients with asthma, active HCV infection is associated with increased bronchodilator responses to inhaled oxitropium bromide. " 01/01/2007 - "The incidence of post-operative pulmonary complications (refractory bronchospasm, pulmonary infection, and acute respiratory failure) was significantly lower in the tiotropium group than in the oxitropium group. "
4.	Allergic Rhinitis 07/01/1998 - "Oxitropium bromide inhalation induced an increase in FEV1 that was significantly greater in allergic rhinitis patients with high serum IgE (155+/-20 mL (mean+/-SEM), p<0.05) than in healthy subjects (64+/-21 mL) or those with allergic rhinitis but low serum IgE (82+/-21 mL, p<0.05). "
5.	Nasal Obstruction 01/01/2008 - "The application of oxitropium bromide resulted in a significant reduction of both watery rhinorrhea and nasal obstruction, but not sneezing or postnasal drip. "

Related Drugs and Biologics

1.	Cholinergic Antagonists (Anticholinergics)
2.	Bronchodilator Agents (Bronchodilators)
3.	Albuterol (Salbutamol)
4.	Formoterol Fumarate (Oxis)
5.	Ipratropium (Ipratropium Bromide)
6.	Tiotropium Bromide (Spiriva)
7.	Theophylline (Theon)
8.	methylatropine
9.	Histamine (Histamine Dihydrochloride)
10.	Acetylcholine (Acetylcholine Chloride)

Related Therapies and Procedures

1.	Metered Dose Inhalers (Metered Dose Inhaler)
2.	Therapeutics