octapeptide-Trp(8)- somatostatin

Also Known As:

somatostatin, octapeptide-Trp(8)-; 8-octapeptide-Trp-SRIH; 8-octapeptide-Trp-somatostatin; 8-octapeptidetryptophan-somatostatin; Cys-Phe-Phe-D-Trp-Lys-Thr-Phe-Cys; Cys-Phe-Phe-D-Trp-Lys-Thr-Phe-D-Cys; ODT8-SS; des-AA(1,2,4,5,12,13)-8-Trp-14-Cys-SS; des-AA(1,2,4,5,12,13)-8-Trp-somatostatin; somatostatin, octapeptidetryptophan(8)-; L-Cysteine, N-(N-(N-(N2-(N-(N-(N-L-cysteinyl-L-phenylalanyl)-L-phenylalanyl)-D-tryptophyl)-L-lysyl)-L-threonyl)-L-phenylalanyl)-

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Hyperthermia 11/01/1981 - "ODT8-SS also produces hyperthermia not associated with an increase in VO2." 06/24/1982 - "Thus, bombesin inhibits VO2 induced by cold and results in hypothermia, ODT8-SS prevents bombesin-induced inhibition of VO2 and bombesin-induced hypothermia and, ODT8-SS increases VO2 and produces hyperthermia in animals at thermoneutral temperatures."
2.	Hypothermia 06/24/1982 - "Thus, bombesin inhibits VO2 induced by cold and results in hypothermia, ODT8-SS prevents bombesin-induced inhibition of VO2 and bombesin-induced hypothermia and, ODT8-SS increases VO2 and produces hyperthermia in animals at thermoneutral temperatures."
3.	Hypoglycemia (Reactive Hypoglycemia) 09/01/1980 - "Insulin-induced hypoglycemia or stress caused significant elevations in plasma catecholamines that were abolished by intracerebroventricular (icv) administration of ODT8-SS. "
4.	Experimental Diabetes Mellitus 09/01/1994 - "ODT8-SS (20 nmol) was ICV-injected (1) in normal dogs (n = 5), and (2) prior to ICV carbachol before (n = 7) and after (n = 6) the induction of alloxan-diabetes. " 09/01/1994 - "After induction of alloxan-diabetes, Rd and MCR did not change with ICV ODT8-SS and carbachol as in normal dogs, but norepinephrine, epinephrine, glucagon, lactate, plasma glucose, and Ra increased, although with the exception of glucagon these increases were much smaller than seen previously with ICV carbachol alone. "
5.	Amnesia (Dissociative Amnesia) 03/01/1984 - "Somatostatin3-6, somatostatin7-10 and ODT8-SS in doses of 0.6, 3 and 6 nM had no effect on the ECS-induced amnesia. "

Related Drugs and Biologics

1.	Lactic Acid (Lactate)
2.	Norepinephrine (Noradrenaline)
3.	Insulin (Novolin)
4.	Glucose (Dextrose)
5.	Glucagon (Glukagon)
6.	Epinephrine (Adrenaline)
7.	Catecholamines
8.	Carbachol (Carbastat)
9.	Bombesin

Related Therapies and Procedures

1.	Induced Hypothermia