hexafluoroacetone

structure; RN given refers to parent cpd

Also Known As:

hexafluoroacetone dihydrate; hexafluoroacetone hydrate; hexafluoroacetone monohydrate; hexafluoroacetone sesquihydrate; hexafluoroacetone trihydrate

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

1.	Atrophy 03/30/1984 - "The disposition and metabolism of [14C]hexafluoroacetone (HFA) were studied in the rat as part of an investigation of the mechanism of HFA-induced testicular atrophy. " 02/01/1984 - "Testicular atrophy was induced in rats by dermal application of hexafluoroacetone (HFA) at 39 or 130 mg/kg/day for 14 days, but not at a dosage of 13 mg/kg/day. " 02/01/1984 - "Ultrastructural alterations in hexafluoroacetone-induced testicular atrophy in the rat." 04/01/1983 - "Rats dosed dermally with 39 or 130 mg/kg/day hexafluoroacetone sesquihydrate (HFA) for 14 days developed moderate or severe testicular atrophy, respectively; rats dosed with 13 mg/kg/day HFA for 14 days did not. "
2.	Hepatitis 08/01/1996 - "Because some aldehydes may covalently bind to proteins and the formation of fluorinated protein adducts has been implicated in immune-mediated hepatitis induced by halothane, the binding of hexafluoroacetone trihydrate to proteins was also investigated. "