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direct brown 95

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Azo Compounds: 333
  - direct brown 95: 1

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 01/01/1978 - "Male rats administered direct brown 95 dye developed neither hepatocellular carcinomas nor neoplastic nodules, but as indicated below, had significant incidences of preneoplastic lesions. " 01/01/1978 - "It is concluded that under the conditions of these 13-week subchronic toxicity studies, direct blue 6 and direct black 38 dyes were carcinogenic in male and female Fischer 344 rats and direct brown 95 was carcinogenic in female rats; all three dyes induced hepatocellular carcinomas and neoplastic nodules in the liver. " 01/01/1978 - "The incidences of hepatocellular carcinomas in female rats administered 3,000 ppm direct blue 6 dye (4/9) and male rats administered 1,500 ppm direct black 38 dye (4/9) were significant (P=0.033) when related to the incidences of the tumors in the corresponding controls (0/10); hepatocellular carcinomas were also observed in two male rats administered 1,500 ppm direct blue 6 dye and in one female rat administered 1,500 ppm direct brown 95 dye. "
2.	Neoplasms (Cancer) 01/01/1978 - "The incidences of hepatocellular carcinomas in female rats administered 3,000 ppm direct blue 6 dye (4/9) and male rats administered 1,500 ppm direct black 38 dye (4/9) were significant (P=0.033) when related to the incidences of the tumors in the corresponding controls (0/10); hepatocellular carcinomas were also observed in two male rats administered 1,500 ppm direct blue 6 dye and in one female rat administered 1,500 ppm direct brown 95 dye. "

Related Drugs and Biologics

1.	Coloring Agents (Dyes)
2.	direct blue 6
3.	direct black 3