do not confuse with DMPO (4',5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin)
Also Known As:
5,5-DMPO; 5,5-dimethyl-1-pyrroline-N-oxide; DMPO-5,5
Networked: 13 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Pisarenko, O I: 1 article (06/2014)
2. Studneva, I M: 1 article (06/2014)
3. Pelogeykina, Yu A: 1 article (06/2014)
4. Shulzhenko, V S: 1 article (06/2014)
5. Serebryakova, L I: 1 article (06/2014)
6. Tskitishvili, O V: 1 article (06/2014)
7. Timoshin, A A: 1 article (06/2014)
8. Konovalova, G G: 1 article (06/2014)
9. Lankin, V Z: 1 article (06/2014)
10. Kubota, Eiro: 1 article (01/2004)

Related Diseases

1. Ischemia
01/01/2000 - "To identify and quantify the types of free radical species generated during ischemia, we used electron paramagnetic resonance (EPR) spectroscopy in the presence and absence of the spin trap, 5,5-dimethyl-1-pyrroline-N-oxide (DMPO). "
01/01/1987 - "The spin trapping agent 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) was used to investigate oxy-radical production in post-ischemic rat hearts previously exposed to 20, 30, or 40 minutes of global ischemia. "
08/01/1991 - "Global hepatic ischemia was induced in 19 rats in four groups: saline solution, phenyl-N-tert-butyl nitrone (PBN), alpha 1-pyridyl-N-oxide N-tert-butyl nitrone (POBN), and 5,5-dimethyl-1-pyrroline-N-oxide (DMPO). "
03/15/2000 - "This article begins with a review of spin trapping detection of oxygen-centered radicals using X-band ESR spectroscopy and then describes the detection of superoxide and hydroxyl radicals by the spin trap 5,5-dimethyl-1-pyrroline-N-oxide and ESR spectroscopy in the perfusate from isolated perfused rat livers subjected to ischemia/reperfusion. "
06/01/2014 - "Infusion of 140 μM A12 or AI before global ischemia improved cardiac function recovery; increased the activity of Cu,Zn superoxide dismutase (Cu,Zn SOD), catalase (CAT), and glutathione peroxidase (GSH-Px); decreased malondialdehyde (MDA) content in reperfused heart; and reduced the formation of hydroxyl radical adduct of the spin trap 5,5-dimethyl-1-pyrroline-N-oxide in the myocardial effluent during early reperfusion compared with these indices in control. "
2. Anoxia (Hypoxia)
3. Temporomandibular Joint Disorders (Temporomandibular Joint Disorder)
4. Photosensitivity Disorders (Photodermatitis)
5. Granuloma

Related Drugs and Biologics

1. Hydroxyl Radical
2. Superoxide Dismutase
3. Malondialdehyde (Propanedial)
4. Glutathione Peroxidase
5. Catalase
6. 2,2-dimethyl-5-hydroxy-1-pyrrolidinyloxy
7. Superoxides (Superoxide)
8. hydroxide ion
9. Cyclooxygenase 2 (Cyclooxygenase-2)
10. Cytochromes c (Cytochrome c)