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anagestone
Also Known As:
17-hydroxy-6 alpha-methylpregn-4-en-20-one
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Pregnanes: 9
Pregnenes: 1
anagestone: 4
Related Diseases
1.
Neoplasms (Cancer)
07/01/1980 - "
Also, 4 dogs that received anagestone acetate plus mestranol at either 0.44 or 1.10 mg/kg/day developed malignant mammary tumors.
"
06/01/1978 - "
Malignant neoplasms were seen in dogs given 10 and 25 times the proposed human dosage of anagestone acetate plus mestranol and 25 times the proposed human dosage of WY-4355 plus mestranol and ethynerone plus mestranol.
"
2.
Hyperplasia
09/01/1977 - "
Generalized cystic hyperplasia of the gallbladder mucosa was seen in a small number of dogs from the anagestone acetate-mestranol group.
"
3.
Diabetes Mellitus
09/01/1977 - "
Diabetes mellitus occurred in 10 dogs from the chloroethynyl norgestrel-mestranol and anagestone acetate-mestranol groups and in 3 monkeys from the ethynerone-mestranol high dose and anagestone acetate-mestranol high dose groups.
"
4.
Noninfiltrating Intraductal Carcinoma (DCIS)
05/01/1988 - "
Of the 40 monkeys administered anagestone acetate and mestranol, 20 (50%) developed proliferative atypias; the atypias ranged from mild to severe and included five resembling intraductal carcinoma in human breast.
"
Related Drugs and Biologics
1.
Mestranol
2.
Acetates (Acetic Acid Esters)
3.
ethynerone
4.
chloroethynyl norgestrel