|1.||Mukhtar, Hasan: 7 articles (01/2015 - 08/2008)|
|2.||Afaq, Farrukh: 7 articles (01/2015 - 08/2008)|
|3.||Andriantsitohaina, Ramaroson: 6 articles (01/2015 - 03/2002)|
|4.||Khan, Naghma: 5 articles (01/2015 - 08/2008)|
|5.||Syed, Deeba N: 4 articles (01/2015 - 08/2008)|
|6.||Marko, Doris: 4 articles (12/2013 - 07/2008)|
|7.||Teller, Nicole: 3 articles (12/2013 - 07/2008)|
|8.||Martin, Sophie: 3 articles (07/2003 - 03/2002)|
|9.||Soleti, Raffaella: 2 articles (01/2015 - 08/2014)|
|10.||Lugnier, Claire: 2 articles (01/2015 - 02/2003)|
01/01/2015 - "Moreover, delphinidin displays anti-angiogenic properties in both in vitro and in vivo angiogenesis models and thereby might prevent the development of tumors associated with excessive vascularization. "
08/01/2014 - "These results suggest that delphinidin is a potential antimetastatic agent that suppresses PMA-induced cancer cell invasion through the specific inhibition of NF-κB-dependent MMP-9 gene expression."
01/01/2013 - "Using these cells, we next determined the effects of delphinidin on cell growth and apoptosis in vitro and on tumor growth and angiogenesis in vivo. "
01/01/2011 - "Delphinidin is also the major bioactive component found in many dietary supplements that are currently consumed as complementary cancer medicine including pomegranate extract. "
10/01/2008 - "We suggest that delphinidin could be developed as an agent for the management of EGFR positive human cancers."
|2.||Breast Neoplasms (Breast Cancer)
01/01/2011 - "The purpose of the current study was to determine the in vitro biological effects of delphinidin on established breast cancer cell lines of varying molecular subtypes in comparison to non-transformed breast epithelial cells. "
10/01/2008 - "In summary, our study identifies a naturally occurring dietary agent delphinidin as an effective inhibitor of EGFR signaling in breast cancer cells. "
10/01/2008 - "In our study, employing EGFR positive breast cancer AU-565 cells and immortalized MCF-10A cells, we evaluated the effect of delphinidin on EGFR and its downstream signaling pathways. "
01/01/2011 - "In summary, the data presented here suggest that single agent delphinidin exhibits growth inhibitory activity in breast cancer cells of various molecular subtypes, but raise concerns regarding potential drug antagonism when used in combination with existing targeted therapies in HER2-overexpressing breast cancer."
01/01/2011 - "In comparison to vehicle control, delphinidin inhibited proliferation (P < 0.05), blocked anchorage-independent growth (P < 0.05), and induced apoptosis (P < 0.05) of ER-positive, triple negative, and HER2-overexpressing breast cancer cell lines with limited toxicity to non-transformed breast epithelial cells. "
|3.||Hepatocellular Carcinoma (Hepatoma)
04/14/2010 - "It was found that whereas cyanidin-3-rutinoside and delphinidin could induce apoptosis in leukemia cells, they caused growth retardation in hepatocellular carcinoma cells (HCC), which was accompanied with a significant cellular vacuolization. "
04/14/2010 - "Delphinidin induces necrosis in hepatocellular carcinoma cells in the presence of 3-methyladenine, an autophagy inhibitor."
03/09/2005 - "Delphinidin, cyanidin, and malvidin exhibited strong growth inhibitory effects against human hepatoma HepG(2), but were less effective against Hep3B. "
10/01/2010 - "To investigate the association of p27 regulation with hypoxia-inducible factor 1-beta (HIF-1β), the level of p27 was analyzed in wild-type mouse hepatoma hepa1c1c7 and Aryl Hydrocarbon Nuclear Translocator (arnt, HIF-1β)-defective mutant BPRc1 cells in the absence and presence of hydrogen peroxide and delphinidin. "
02/05/2003 - "The effects of pretreatment with the anthocyanins delphinidin, cyanidin, and their glycoside and rutinoside derivatives against induction of DNA damage induced by tert-butyl-hydroperoxide (TBHP) were evaluated in rat smooth muscle and in rat hepatoma cell lines using alkaline single cell gel electrophoresis (Comet test). "
|4.||Glioblastoma (Glioblastoma Multiforme)
11/15/2015 - "Direct transfection of miR-137 mimics is more effective than DNA demethylation of miR-137 promoter to augment anti-tumor mechanisms of delphinidin in human glioblastoma U87MG and LN18 cells."
01/01/2007 - "In this work, we report that the aglycons of the most abundant anthocyanins in fruits, cyanidin (Cy), delphinidin (Dp), and petunidin (Pt), act as potent inhibitors of glioblastoma cell migration. "
|4.||DNA (Deoxyribonucleic Acid)
|5.||Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
|1.||Heterologous Transplantation (Xenotransplantation)