delphinidin

12/07/2021 - "(4) Conclusions: sEVs may be considered as a promising approach to deliver delphinidin to target angiogenesis-related diseases, including cancer and pathologies associated with excess vascularization."
01/12/2021 - "Delphinidin (D) has been reported to be cytotoxic for cancer cell lines. "
12/12/2019 - "Thus, we aimed to investigate the anti-cancer activity of delphinidin in CRC cells and the underlying molecular mechanisms. "
12/01/2017 - "We investigated the suppressive effect of delphinidin on the cancer migration and invasion. "
12/01/2017 - "However, the possible role of delphinidin in the cancer migration and invasion is unclear. "

01/01/2011 - "The purpose of the current study was to determine the in vitro biological effects of delphinidin on established breast cancer cell lines of varying molecular subtypes in comparison to non-transformed breast epithelial cells. "
10/01/2008 - "In summary, our study identifies a naturally occurring dietary agent delphinidin as an effective inhibitor of EGFR signaling in breast cancer cells. "
10/01/2008 - "In our study, employing EGFR positive breast cancer AU-565 cells and immortalized MCF-10A cells, we evaluated the effect of delphinidin on EGFR and its downstream signaling pathways. "
01/01/2022 - "We acquired the know therapeutic targets of delphinidin and obtained differentially expressed genes (DEGs) of breast cancer using RTCGA. "
01/01/2022 - "We further studied the effect of delphinidin on breast cancer cells through comprehensive network pharmacology, cellular and molecular experiments. "

12/01/2017 - "These results suggest that the anti-inflammatory effect of delphinidin alleviated inflammation in the SCI rat model via alleviation of the intramedullary spinal pressure through the NF-κB and p38-MAPK signaling pathways."
01/01/2017 - "Together, we propose that delphinidin, by acting on ERα via multiple cellular targets, may represent a new approach against chronic inflammation associated with T lymphocyte activation, proliferation and differentiation, in patients with cardiovascular risk factors."
02/01/2015 - "To determine whether topical application of delphinidin can modulate pathological markers of psoriasiform lesions in flaky skin mice and if this is associated with increased epidermal differentiation and a reduction in proliferation and inflammation. "
02/01/2015 - "Topical application of delphinidin reduces psoriasiform lesions in the flaky skin mouse model by inducing epidermal differentiation and inhibiting inflammation."
01/01/2015 - "To investigate the effect of delphinidin (0-20 μM; 2-5 days) on psoriatic epidermal keratinocyte differentiation, proliferation and inflammation using a three-dimensional reconstructed human psoriatic skin equivalent (PSE) model. "

02/08/2023 - "To investigate the function and regulatory mechanisms of delphinidin in the treatment of hepatocellular carcinoma. "
01/01/2019 - "Delphinidin inhibits epidermal growth factor-induced epithelial-to-mesenchymal transition in hepatocellular carcinoma cells."
04/14/2010 - "It was found that whereas cyanidin-3-rutinoside and delphinidin could induce apoptosis in leukemia cells, they caused growth retardation in hepatocellular carcinoma cells (HCC), which was accompanied with a significant cellular vacuolization. "
04/14/2010 - "Delphinidin induces necrosis in hepatocellular carcinoma cells in the presence of 3-methyladenine, an autophagy inhibitor."
03/09/2005 - "Delphinidin, cyanidin, and malvidin exhibited strong growth inhibitory effects against human hepatoma HepG(2), but were less effective against Hep3B. "

01/11/2017 - "The purpose of this study was to determine the preventive mechanism of delphinidin on disuse muscle atrophy. "
01/11/2017 - "Delphinidin intake may prevent disuse muscle atrophy by inducing miR-23a expression and suppressing MuRF1 expression."
01/11/2017 - "Delphinidin Prevents Muscle Atrophy and Upregulates miR-23a Expression."
08/01/2016 - "Thus, delphinidin may prevent unloading-mediated muscle atrophy. "
08/01/2016 - "We examined the effects of delphinidin on muscle atrophy. "