|1.||Geschwind, Jean-Francois H: 11 articles (06/2013 - 07/2002)|
|2.||Pedersen, Peter L: 10 articles (04/2015 - 07/2002)|
|3.||Buijs, Manon: 8 articles (06/2013 - 01/2008)|
|4.||Ganapathy-Kanniappan, Shanmugasundaram: 7 articles (12/2014 - 10/2008)|
|5.||Vali, Mustafa: 7 articles (02/2011 - 01/2007)|
|6.||Ko, Young H: 6 articles (07/2014 - 07/2002)|
|7.||Liu, Hao: 5 articles (10/2015 - 09/2013)|
|8.||Vossen, Josephina A: 5 articles (02/2011 - 01/2008)|
|9.||Jiang, Chenchen: 4 articles (10/2015 - 09/2013)|
|10.||Ota, Shinichi: 4 articles (06/2013 - 12/2009)|
09/12/2014 - "Clinical research is currently exploring the validity of the anti-tumor candidate 3-bromopyruvate (3-BP) as a novel treatment for several types of cancer. "
08/01/2010 - "3-bromopyruvate: a new targeted antiglycolytic agent and a promise for cancer therapy."
06/01/2015 - "Correction to "Targeting of VX2 Rabbit Liver Tumor by Selective Delivery of 3-Bromopyruvate: A Biodistribution and Survival Study"."
05/01/2012 - "Due to the known liver toxicity of 3-bromopyruvate in animal models given large doses of 3-bromopyruvate, confirmed in this study, we decided to test the chemopreventive activity of aerosolized 3-bromopyruvate in the same lung tumor model. "
05/01/2012 - "In this study, we investigated the chemopreventive activity of 3-bromopyruvate in a mouse lung tumor model. "
12/15/2014 - "This study characterized the therapeutic efficacy of a systemically administered formulation of 3-bromopyruvate (3-BrPA), microencapsulated in a complex with β-cyclodextrin (β-CD), using an orthotopic xenograft mouse model of pancreatic ductal adenocarcinoma (PDAC). "
01/01/2015 - "The objective of this study was to evaluate the expression levels of glycolytic markers, especially hexokinase-2 (HK2), using a three-dimensional multicellular spheroid model of human ovarian adenocarcinoma (SKOV-3) cells and to develop an epidermal growth factor receptor-targeted liposomal formulation for improving inhibition of HK2 and the cytotoxicity of 3-bromopyruvate (3-BPA). "
|3.||Neoplasm Metastasis (Metastasis)
10/22/2013 - "To evaluate the metastasis and survival of an intra-arterial infusion of 3-bromopyruvate (3-BrPA) on hepatic VX2 tumor in rabbits. "
10/22/2013 - "[Effects of intra-arterial infusion of 3-bromopyruvate on metastases and survival benefit of hepatic VX2 tumor in rabbits]."
01/01/2008 - "Development of a new orthotopic animal model of metastatic liver cancer in the rabbit VX2 model: effect on metastases after partial hepatectomy, intra-arterial treatment with 3-bromopyruvate and chemoembolization."
07/15/2014 - "3-bromopyruvate inhibited in vivo tumor engraftment and growth on chicken eggs and mice and enhanced the efficacy of gemcitabine by influencing the expression of markers of proliferation, apoptosis, self-renewal, and metastasis. "
|4.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/01/2014 - "Our previous study demonstrated inhibitory effects of 3-bromopyruvate (3-BrPA) on pleural mesothelioma. "
02/01/2012 - "Experimental results using 3-bromopyruvate in mesothelioma: in vitro and in vivo studies."
04/01/2009 - "Novel therapy for malignant pleural mesothelioma based on anti-energetic effect: an experimental study using 3-Bromopyruvate on nude mice."
04/01/2009 - "The effect of 3-Bromopyruvate (3-BrPA) alone or associated to cisplatin on nude mice presenting intraperitoneal carcinomatosis developed after intraperitoneal injection of human mesothelioma cells (MSTO-211H) was investigated. "
|1.||Pyruvic Acid (Pyruvate)
|4.||Dichloroacetate (Dichloroacetic Acid)
|8.||Epidermal Growth Factor Receptor (EGF Receptor)
|1.||Heterologous Transplantation (Xenotransplantation)
|5.||Drug Therapy (Chemotherapy)