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benzoxazolone

RN given refers to parent cpd; structure

Also Known As:

2-benzoxazolinone; benzoxalinone; benzoxazolin-2(3H)-one; benzoxazolin-2-one; benzoxazolone zinc salt; benzoxazolone-2

Networked: 9 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzoxazoles: 68
      - benzoxazolone: 9

Experts

1.	Chen, Huan: 1 article (04/2021)
2.	Fan, Zhenya: 1 article (04/2021)
3.	Lei, Yanqi: 1 article (04/2021)
4.	Li, Lingyun: 1 article (04/2021)
5.	Liu, Wenchao: 1 article (04/2021)
6.	Ma, Bing: 1 article (04/2021)
7.	Ma, Zequn: 1 article (04/2021)
8.	Xu, Long: 1 article (04/2021)
9.	Yin, Zhechang: 1 article (04/2021)
10.	Zhang, Xiaonan: 1 article (04/2021)

Related Diseases

1.	Liver Cirrhosis (Hepatic Cirrhosis) 07/01/2015 - "This study was designed to investigate the protective effects of Acanthus ilicifolius alkaloid A [4-hydroxy-2-benzoxazolone (HBOA)] and its acetylated derivatives including 4-acetoxy-2-benzoxazolone (TC-2) and 3-acetyl-4-acetoxy-2-benzoxazolone (TC-3) on carbon tetrachloride (CCl4 )-induced liver fibrosis in rats. "
2.	Alzheimer Disease (Alzheimer's Disease) 02/15/2021 - "In this study, four series of compounds with benzoxazolone and benzothiazolone cores were designed, synthesized and evaluated as multifunctional agents against Alzheimer's disease (AD). " 02/15/2021 - "Design, synthesis and biological evaluation of new benzoxazolone/benzothiazolone derivatives as multi-target agents against Alzheimer's disease." 06/01/2011 - "Design, synthesis and biological evaluation of new 2-benzoxazolinone derivatives as potential cholinesterase inhibitors for therapy of alzheimer's disease."
3.	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/01/2020 - "Herein, we describe the lead optimization studies of benzoxazolone carboxamides resulting in piperidine 22m, where we demonstrated target engagement in two animal models of neuropathic lysosomal storage diseases (LSDs), Gaucher's and Krabbe's diseases. "
4.	Acute Lung Injury 11/01/2020 - "Design and synthesis of new disubstituted benzoxazolone derivatives that act as iNOS inhibitors with potent anti-inflammatory activity against LPS-induced acute lung injury (ALI)."
5.	Diabetes Complications 12/01/2018 - "Identification of 2-benzoxazolinone derivatives as lead against molecular targets of diabetic complications."

Related Drugs and Biologics

1.	Carbon Tetrachloride (Tetrachloromethane)
2.	Alkaloids
3.	piperidine
4.	Caspase 3 (Caspase-3)
5.	Cytochromes c (Cytochrome c)
6.	Cholinesterase Inhibitors (Anticholinesterases)
7.	Chlorzoxazone

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Aftercare (After-Treatment)