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LC 6

RN given refers to (trans)-isomer; structure
Also Known As:
LC-6; trans-2,3b,4,5,7,8b,9,10-octahydronaphtho(1,2-c:5,6-c')dipyrazole
Networked: 22 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ogata, Etsuro: 5 articles (05/2011 - 10/2003)
2. Onuma, Etsuro: 5 articles (05/2011 - 10/2003)
3. Yamada-Okabe, Hisafumi: 4 articles (05/2011 - 09/2004)
4. Sato, Koh: 3 articles (06/2005 - 10/2003)
5. Fujihara, Hiroaki: 2 articles (05/2011 - 01/2007)
6. Kawasaki, Makoto: 2 articles (05/2011 - 01/2007)
7. Ueta, Yoichi: 2 articles (05/2011 - 01/2007)
8. Hashimoto, Hirofumi: 2 articles (05/2011 - 01/2007)
9. Takuwa, Yoh: 2 articles (05/2011 - 01/2007)
10. Azuma, Yumiko: 2 articles (01/2007 - 06/2005)

Related Diseases

1. Lung Neoplasms (Lung Cancer)
2. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
3. Pancreatic Neoplasms (Pancreatic Cancer)
4. Neoplasms (Cancer)
5. Carcinoma (Carcinomatosis)
10/01/2003 - "The humanized anti-PTHrP antibody was administered intravenously to HHM model animals bearing tumors such as LC-6 human lung carcinoma. "
05/01/1994 - "Tumor regression was observed in mice bearing LC-6 lung, St-4 and St-40 stomach, Li-7 liver, PAN-2 pancreas, and MX-1 breast carcinomas. "
10/01/1991 - "Pathologic examination of cases of UIP with LC (6 squamous cell carcinomas, 5 small cell carcinomas, 4 adenocarcinomas, and 3 large cell carcinomas, 2 of which showed pulmonary double carcinoma revealing a slight correlation between fibrosis and primary site of LC and a slightly greater correlation of squamous cell carcinoma and small cell carcinoma to smoking habits and inhalation of dust. "
03/10/2005 - "6ab showed significant antitumor activity against five human tumor xenografts such as GL07 (glioma), St-4 (stomach carcinoma), LC6 (lung carcinoma), DLD-1 (colon carcinoma) and A375 (melanoma) in nude mice and also showed complete tumor growth inhibition with the LC-6 xenograft in nude rats following oral administration once a day for 14 days at 5 mg/kg without any body weight loss."
03/01/1994 - "FR901228 (ip) prolonged the life of mice bearing such murine ascitic tumors as P388 and L1210 leukemias and B16 melanoma, and inhibited (iv) the growth of murine solid tumors (Colon 38 carcinoma, M5076 reticulum cell sarcoma and Meth A fibrosarcoma) and human solid tumors (Lu-65 and LC-6 lung carcinomas, and SC-6 stomach adenocarcinoma) implanted in normal and nude mice, respectively. "

Related Drugs and Biologics

1. Parathyroid Hormone-Related Protein
2. Calcium
3. K 76 carboxylic acid
4. Leptin
5. Nimustine
6. Messenger RNA (mRNA)
7. Antigens
8. VGA1155
9. 5- (3- (4- (octadecyloxy)phenyl)propionylamino)- 2,4'- oxydibenzoic acid
10. KF41399

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Oral Administration