IMET 98-69

Also Known As:

3-(di-(2-hydroxyethyl)amino)acetophenone (4,5-diphenyloxazol-2-yl)hydrazone; zimet 98-69; ethanone, 1-(3-(bis(2-hydroxyethyl)amino)phenyl)-, (4,5-diphenyl-2-oxazolyl)hydrazone

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - IMET 98-69: 3

Related Diseases

1.	Encephalitis (Encephalitis, Rasmussen) 01/01/1977 - "Out of a series of eleven related hetarylhydrazones four derivatives (ZIMET 124/73, ZIMET 38/74, ZIMET 44/69, and IMET 98/69), after subcutaneous administration (0.5 mmole/kg per injection), were found to possess significant antiviral activity against rapidly progressing and highly lethal Mengo virus encephalitis in mice. " 01/01/1978 - "3-[Bis-(2-hydroxyethyl)-amino]-acetophenone-[4.5-diphenyl-oxazolyl-(2)]-hydrazone (IMET 98/69) was found to afford maximum "rates of protection" in intraperitoneally (i.p.) or intranasally (i.n.) induced Mengo virus encephalitis in mice when administered once daily at doses of 1 mmole/kg (456.5 mg/kg) subcutaneously (s.c.) or 4 mmoles/kg (1 826 mg/kg) perorally (p.o.). " 01/01/1978 - "Effect of 3-[bis-(2-hydroxyethyl)-amino]-acetophenone-[4.5-diphenyl-oxazolyl-(2)]-hydrazone (IMET 98/69) on lethal mengo virus encephalitis."
2.	Infections 11/01/1979 - "The potential in vivo antiviral activity of 3-[bis-(2-hydroxyethyl)-amino]-acetophenone-[4,5-diphenyl-oxazolyl-(2)]-hydrazone (IMET 98/69) was evaluated on model infections in mice. "

Related Drugs and Biologics

1.	Hydrazones
2.	Antiviral Agents (Antivirals)
3.	acetophenone
4.	diphenyl (biphenyl)
5.	ZIMET 38-74