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selenonorcholesterol
adrenal radioisotope scanning agents
Also Known As:
(75)selenonorcholesterol; 6-methyl-(75)selenomethyl-19-norcholest-5(10)-en-3 beta-ol; Scintadren; 19-Norcholest-5(10)-en-3-ol, 6-((methylseleno-(75)Se)methyl) (3beta,6beta)
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Cholestanes
Sterols: 2245
Cholesterol: 67133
selenonorcholesterol: 3
Cholestenes
Cholesterol: 67133
selenonorcholesterol: 3
Lipids: 114793
Membrane Lipids: 1591
Sterols: 2245
Cholesterol: 67133
selenonorcholesterol: 3
Related Diseases
1.
Hyperaldosteronism (Conn Syndrome)
10/30/1982 - "
When the results of Scintadren imaging and CT are pooled, the accuracy in lateralizing APAs and differentiating APA from IAH as a cause of Conn's syndrome is 100%.
"
07/01/1980 - "
[Adrenal scintigraphy with 75Se-Scintadren: localizing diagnosis of adrenal adenoma in primary aldosteronism (author's transl)].
"
10/30/1982 - "
Six consecutive patients with biochemically proven primary aldosteronism (4 with unilateral aldosteronomas and 2 with bilateral hyperplasia) underwent imaging with 75Se-selenomethyl-nor-cholesterol (Scintadren; Radiochemical Centre, Amersham, UK) and computed tomography (CT) of the adrenal glands to aid in lateralizing unilateral aldosterone-producing adenomas (APA) and to differentiate APA from idiopathic adrenal hyperplasia (IAH).
"
2.
Adenoma (Adenomas)
07/01/1980 - "
[Adrenal scintigraphy with 75Se-Scintadren: localizing diagnosis of adrenal adenoma in primary aldosteronism (author's transl)].
"
10/30/1982 - "
Six consecutive patients with biochemically proven primary aldosteronism (4 with unilateral aldosteronomas and 2 with bilateral hyperplasia) underwent imaging with 75Se-selenomethyl-nor-cholesterol (Scintadren; Radiochemical Centre, Amersham, UK) and computed tomography (CT) of the adrenal glands to aid in lateralizing unilateral aldosterone-producing adenomas (APA) and to differentiate APA from idiopathic adrenal hyperplasia (IAH).
"
3.
Hyperplasia
10/30/1982 - "
Six consecutive patients with biochemically proven primary aldosteronism (4 with unilateral aldosteronomas and 2 with bilateral hyperplasia) underwent imaging with 75Se-selenomethyl-nor-cholesterol (Scintadren; Radiochemical Centre, Amersham, UK) and computed tomography (CT) of the adrenal glands to aid in lateralizing unilateral aldosterone-producing adenomas (APA) and to differentiate APA from idiopathic adrenal hyperplasia (IAH).
"
4.
Cushing Syndrome
05/28/1983 - "
Measurement of 75Se-cholesterol (Scintadren) uptake and computed tomography (CT) of the adrenal glands were compared as a means of differentiating the cause of Cushing's syndrome in 11 patients over a 2-year period.
"
05/28/1983 - "
Scintadren imaging and CT are useful non-invasive procedures for differentiating local adrenal disease from ACTH-dependent disease as the cause of Cushing's syndrome and should be the initial investigations once a firm clinical and biochemical diagnosis of Cushing's syndrome has been made.
"
05/28/1983 - "
Quantitative Scintadren imaging differentiated adrenocorticotrophic hormone (ACTH)-dependent disease from local adrenocortical lesions as the cause of Cushing's syndrome in all the patients studied.
"
Related Drugs and Biologics
1.
Aldosterone
2.
Adrenocorticotropic Hormone (ACTH)