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poly(2'-O-methylcytidylic acid)

Also Known As:

poly(2'-methylcytidilate); poly(rCm)

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Polyribonucleotides: 23
      - Poly C: 296
        poly(2'-O-methylcytidylic acid): 1

Related Diseases

1.

Breast Neoplasms (Breast Cancer)

02/01/1977 - "Thus like these viral enzymes, the purified human breast cancer DNA polymerase exhibits the following three features that together distinguish the known viral reverse transcriptases from normal cellular DNA polymerases: (i) a strong preference for oligo(dT)-poly(rA) over oligo(dT)-poly(dA) as a template for the synthesis of poly(dT); (ii) the acceptance of the highly specific oligo(dG)-poly(rCm) as a template for the formation of poly(dG); (iii) the ability to use a viral RNA (AMV) as a template to fashion a faithful DNA complementary copy; and (iv) its preference for Mg++ over Mn++. "

Related Drugs and Biologics

1.	Complementary DNA (cDNA)
2.	Viral RNA
3.	DNA-Directed RNA Polymerases (RNA Polymerase)
4.	Poly T
5.	Poly A
6.	Enzymes
7.	DNA-Directed DNA Polymerase (Polymerases, DNA)
8.	oligodeoxyguanylic acid
9.	oligo (dT)
10.	poly(dG)