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photomirex

major photodecomposition product of mirex (dodecachloro)

Also Known As:

8-monohydromirex; 1,2,3,4,5,5,6,7,9,10,10- undecachloropentacyclo(5.3.0.0.0.0)decane

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - Mirex: 49
        photomirex: 4

Related Diseases

1.	Body Weight (Weight, Body) 01/01/1980 - "Photomirex (8-monohydromirex) was administered to female Sprague-Dawley rats at dietary levels of 0.2, 1.0, 5.0, 25.0 and 125 ppm. Food intake and body weight gain were significantly depressed at the 125 ppm level in the 28- but not in the 90-day study. " 01/01/1979 - "Adult New Zealand white does were intubated orally with single daily doses of 0, 5, or 10 mg of photomirex (8-monohydromirex) per kg body weight from the 6th through to the 18th day of gestation. " 07/01/1980 - "Daily oral administration of photomirex caused a dose-dependent loss of body weight. " 01/01/1981 - "The lower body weight gain in animals fed 50 ppm photomirex and 50 ppm mirex observed after 28 days on the test was not evidence after 12 weeks on the clean diet or thereafter. "
2.	Hypertrophy 01/01/1981 - "Liver hypertrophy was observed in the 5.0-ppm and 50-ppm photomirex groups after 28 days and persisted in the highest dose group for 24 weeks on clean diet. "
3.	Hepatomegaly 01/01/1980 - "Dose-dependent histotoxic effects were observed in liver and thyroid at and above 1 ppm; hepatomegaly was observed at 25.0 and 125 ppm. These results indicate that photomirex was approximately five times more toxic than mirex in terms of liver histology. "

Related Drugs and Biologics

1.	Mirex

Related Therapies and Procedures

1.	Oral Administration