|1.||Mecham, Robert P: 2 articles (09/2015 - 09/2008)|
|2.||Lemaire, Raphael: 2 articles (06/2005 - 03/2004)|
|3.||Shipley, J Michael: 2 articles (06/2005 - 03/2004)|
|4.||Korn, Joseph H: 2 articles (06/2005 - 03/2004)|
|5.||Lafyatis, Robert: 2 articles (06/2005 - 03/2004)|
|6.||Dabovic, Branka: 1 article (11/2015)|
|7.||Ramirez, Francesco: 1 article (11/2015)|
|8.||Zilberberg, Lior: 1 article (11/2015)|
|9.||Rifkin, Daniel B: 1 article (11/2015)|
|10.||Phoon, Colin K L: 1 article (11/2015)|
|1.||Marfan Syndrome (Marfan's Syndrome)
05/01/1997 - "The gene for microfibril-associated protein-1 (MFAP1) is located several megabases centromeric to FBN1 and is not mutated in Marfan syndrome."
02/01/2008 - "Marfan syndrome type I (MFS1, MIM #154700) is caused by mutations in FBN1 encoding fibrillin-1, which is a major microfibrillar protein of elastic system fibers. "
08/01/2002 - "Marfan syndrome (MFS) and other type 1 fibrillinopathies result from mutations in the FBN1 gene, which encodes the connective-tissue microfibrillar protein fibrillin 1. Attempts at correlating genotype with phenotype have suggested considerable heterogeneity. "
01/01/1993 - "Abnormalities of the microfibrillar protein fibrillin (Fib) have been reported in Marfan syndrome (MFS). "
07/19/1990 - "Indirect-immunofluorescence studies of skin and cultured dermal fibroblasts from patients with the Marfan syndrome demonstrate apparent deficiency of one element of connective tissue--the microfibrillar-fiber system--in assays using specific antibodies against fibrillin, a major microfibrillar protein. "
06/01/2005 - "It also suggests that MAGP-2 might mediate skin fibrosis in TSK mice and in patients with scleroderma."
06/01/2005 - "Increased expression of type I collagen induced by microfibril-associated glycoprotein 2: novel mechanistic insights into the molecular basis of dermal fibrosis in scleroderma."
03/01/2004 - "Tsk-Fbn1 altered ECM organization and caused fibrosis by affecting the deposition of MAGP-2 or other Fbn-1-associated proteins. "
05/01/2015 - "Furthermore, we confirmed the altered expression of microfibril-associated glycoprotein 4 (MFAP4), lumican (LUM), and collagen alpha-1(XIV) chain (COL14A1) in association to hepatic fibrosis. "
06/01/2005 - "Previous studies have suggested that fibrillin 1 mediates skin fibrosis via its interface with associated microfibrillar proteins and type I collagen; in particular, microfibril-associated glycoprotein 2 (MAGP-2), an extracellular matrix protein that binds to fibrillins and the alphavbeta3 integrin, is increased in TSK mouse and human scleroderma skin. "
|3.||Abdominal Aortic Aneurysm
09/01/2003 - "The role of a putative microfibrillar protein (80 kDa) in abdominal aortic aneurysm disease."
09/01/2003 - "We previously have reported the partial amino acid sequence of a putative aortic autoantigen in patients with abdominal aortic aneurysm (AAA) disease that has homologies with an elastin-associated microfibrillar protein found in aorta of pigs. "
02/06/1996 - "A microfibrillar protein (40 kDa) purified from the adventitia of the human abdominal aorta is immunoreactive with IgG harvested from the wall of abdominal aortic aneurysms. "
05/01/1997 - "We have recently purified and partially sequenced a microfibrillar protein from human aortic adventitia (aneurysm-associated antigenic protein, 40 kDa [AAAP-40]) that is immunoreactive with immunoglobulin (IgG) from the wall of abdominal aortic aneurysms (AAAs). "
|4.||Aortic Aneurysm (Aneurysm, Aortic)
08/01/1997 - "We have purified and partially sequenced a protein from the adventitia of the human aorta (aortic aneurysm antigenic protein 40 kDa; AAAP-40) that has homologies to bovine aortic microfibril-associated glycoprotein (MAGP-36). "
11/10/2015 - "Marfan syndrome (MFS) is an autosomal dominant disorder of connective tissue, caused by mutations of the microfibrillar protein fibrillin-1, that predisposes affected individuals to aortic aneurysm and rupture and is associated with increased TGFβ signaling. "
02/06/1996 - "Partial amino acid sequence of a novel 40-kDa human aortic protein, with vitronectin-like, fibrinogen-like, and calcium binding domains: aortic aneurysm-associated protein-40 (AAAP-40) [human MAGP-3, proposed]."
05/24/2006 - "One of these differentially expressed transcripts was a homolog of microfibril-associated glycoprotein 4 (magp4), a putative causative gene for the human inherited disease, Smith-Magenis syndrome (SMS), for which facial defects are among the phenotypic features. "
04/01/1995 - "The gene for a human microfibril-associated glycoprotein is commonly deleted in Smith-Magenis syndrome patients."
04/01/1995 - "Smith-Magenis syndrome (SMS) is a clinically recognizable multiple congenital anomaly/mental retardation syndrome associated with deletion of chromosome 17p11.2. Here we report the identification of a novel gene encoding a human microfibril-associated glycoprotein (MFAP4), which has been mapped to the SMS region. "
|2.||Proteins (Proteins, Gene)
|4.||Collagen Type I (Type I Collagen)
|6.||Immunoglobulin G (IgG)
|8.||Integrin beta3 (GPIIIa)
|9.||Collagen Type IV (Type IV Collagen)
|1.||Renal Dialysis (Hemodialysis)