|1.||Firestone, Gary L: 22 articles (11/2014 - 02/2002)|
|2.||Bjeldanes, Leonard F: 20 articles (11/2012 - 02/2002)|
|3.||Mullins, John J: 16 articles (12/2014 - 10/2005)|
|4.||Sarkar, Fazlul H: 16 articles (01/2012 - 02/2002)|
|5.||Mitchell, Kenneth D: 14 articles (10/2013 - 10/2005)|
|6.||Li, Yiwei: 9 articles (06/2010 - 04/2003)|
|7.||Weng, Jing-Ru: 8 articles (11/2013 - 08/2007)|
|8.||Sundar, Shyam N: 7 articles (01/2014 - 12/2006)|
|9.||Williams, David E: 7 articles (07/2013 - 07/2003)|
|10.||Rahman, K M Wahidur: 7 articles (06/2010 - 02/2002)|
02/01/2000 - "Analysis of the biological effects of the Cruciferae diet has helped start clinical studies of indole-3-carbinol as an antitumor and anticarcinogenic remedy for patients with a high risk of tumor diseases."
11/15/2013 - "Indole-3-carbinol (I3C) is a broadly targeted phytochemical shown to prevent carcinogenesis in animal studies and to suppress the proliferation of cancer cells of human breast, colon, prostate, and endometrium. "
07/01/2013 - "As in previous studies, indole-3-carbinol (I3C, feed to the dam at 100, 500 or 1000ppm), derived from cruciferous vegetables, dose-dependently reduced lung tumor multiplicity and also increased offspring survival. "
03/01/2008 - "This study was designed to investigate the effect of indole-3-carbinol (I3C) in cell lines and on PC tumor growth in mice when given as a therapeutic and as a preventive treatment. "
07/26/2007 - "Indole-3-carbinol (I3C) is a naturally occurring anticancer agent and has entered clinical trials for cancer prevention. "
|2.||Breast Neoplasms (Breast Cancer)
05/01/2013 - "Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies."
08/01/2005 - "We completed a phase I trial of indole-3-carbinol (I3C) in 17 women (1 postmenopausal and 16 premenopausal) from a high-risk breast cancer cohort. "
01/01/1997 - "Dose-ranging study of indole-3-carbinol for breast cancer prevention."
01/01/2012 - "Induction of endoplasmic reticulum stress response by the indole-3-carbinol cyclic tetrameric derivative CTet in human breast cancer cell lines."
08/05/2010 - "1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells."
|3.||Prostatic Neoplasms (Prostate Cancer)
06/01/2013 - "Indole-3-carbinol and 3',3'-diindolylmethane modulate androgen's effect on C-C chemokine ligand 2 and monocyte attraction to prostate cancer cells."
07/01/2008 - "Indole-3-carbinol as a chemoprotective agent in breast and prostate cancer."
08/15/2007 - "A potent indole-3-carbinol derived antitumor agent with pleiotropic effects on multiple signaling pathways in prostate cancer cells."
01/01/2005 - "Anti-carcinogenic and anti-metastatic properties of indole-3-carbinol in prostate cancer."
12/01/2004 - "Indole-3-carbinol and prostate cancer."
|4.||Hepatocellular Carcinoma (Hepatoma)
01/01/2015 - "Indole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells via suppression of microRNA-21 and upregulation of phosphatase and tensin homolog."
10/01/2011 - "The effect of diindolylmethane, a natural compound derived from indole-3-carbinol in cruciferous vegetables, on cytosolic Ca(2+) concentrations ([Ca(2+)](i)) and viability in HA59T human hepatoma cells is unclear. "
12/01/2002 - "The aim of this study was to explore the roles of the cruciferous vegetable-derived indoles, indole-3-carbinol (I3C) and indolo[3.2-b]carbazole (ICZ), on the regulation of QR in both murine (Hepa-1) and human (HepG2) hepatoma cells. "
11/01/2009 - "Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma."
03/21/2013 - "The present study investigated and compared the potential chemosensitizing effect of indole-3-carbinol (I3C) and epigallocatechin-3-gallate (EGCG) on TRAIL-induced apoptosis in human hepatocellular carcinoma (HCC) HepG2 cells as well as the possible mechanisms underlying these modulatory effects, particularly their effects on TRAIL death receptors (DR), Bcl-2 and c-FLIP proteins expression. "
04/01/2011 - "This study investigated the effects of indole-3-carbinol (I3C), a cruciferous vegetable derivative, on obesity and its associated factors in high-fat-diet-induced obese (DIO) mice. "
12/01/2012 - "Indole-3-carbinol prevents diet-induced obesity through modulation of multiple genes related to adipogenesis, thermogenesis or inflammation in the visceral adipose tissue of mice."
09/01/2013 - "Indole-3-carbinol (I3C), a monomer component extracted from leaves and stems of cruciferous vegetables, has inhibitory effects on tumors, obesity, and liver fibrosis, but its effects on the development of cardiac remodeling remain completely unknown. "
12/01/2011 - "This study investigated the effects of indole-3-carbinol (I3C), a compound from cruciferous vegetables, on various parameters related to obesity, in particular, the parameters of infiltration by macrophages and of inflammatory cytokines expressed during the co-culture of adipocytes and macrophages. "
|4.||Heterologous Transplantation (Xenotransplantation)