formyl-leurosine

RN given refers to (3'alpha,4'alpha)-isomer

Also Known As:

F-leurosine; formyl leurosine; formyl-leurosine, sulfate (1:1), (3'alpha,4'alpha)-isomer; formyl-leurosine, sulfate (2:1), (3'alpha,4'alpha)-isomer; Vincaleukoblastine, 4'-deoxy-3',4'-epoxy-22-oxo-, (3'alpha,4'alpha)-

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - Secologanin Tryptamine Alkaloids: 81
      - Vinca Alkaloids: 463
        formyl-leurosine: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Vinca Alkaloids: 463
        formyl-leurosine: 4
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        Secologanin Tryptamine Alkaloids: 81
        Vinca Alkaloids: 463
        formyl-leurosine: 4

Related Diseases

1.	Wallerian Degeneration 07/01/1979 - "Leg paralysis and wallerian degeneration of sciatic nerve fibres have been produced in rats by intraneural injection of 0.5, 1 or 5 micrograms of vincristine (VCR) or formyl leurosine (FLR) dissolved in 5 microliters of saline. " 07/01/1979 - "Leg paralysis and wallerian degeneration of sciatic nerve fibres have been produced in rats by intraneural injection of 0.5, 1 or 5 microgram of vincristine (VCR) or formyl leurosine (FLR) dissolved in 5 microliter of saline. "
2.	Paralysis (Palsy) 07/01/1979 - "Leg paralysis and wallerian degeneration of sciatic nerve fibres have been produced in rats by intraneural injection of 0.5, 1 or 5 micrograms of vincristine (VCR) or formyl leurosine (FLR) dissolved in 5 microliters of saline. " 07/01/1979 - "Leg paralysis and wallerian degeneration of sciatic nerve fibres have been produced in rats by intraneural injection of 0.5, 1 or 5 microgram of vincristine (VCR) or formyl leurosine (FLR) dissolved in 5 microliter of saline. "
3.	Wounds and Injuries (Trauma) 01/01/1985 - "The later phase of F-leurosine action (greater than 1 hour) was associated with a permanent circulatory depression, a compromised coronary autoregulatory capacity, and serious histological injuries in the heart. "
4.	Neoplasms (Cancer) 01/01/1980 - "P388 tumor sensitive to vincristine (VCR) and formyl-leurosine (F-leu) incorporates three times more VCR and four times more F-leu than the resistant line of the same tumor. "

Related Drugs and Biologics

1.	Vincristine (Oncovin)