|1.||Artlett, Carol M: 4 articles (11/2013 - 01/2010)|
|2.||Loughlin, Danielle T: 3 articles (01/2011 - 01/2010)|
|3.||Sassi-Gaha, Sihem: 2 articles (11/2013 - 03/2010)|
|4.||Kappler, Frank: 2 articles (03/2010 - 06/2003)|
|5.||Beisswenger, Paul J: 2 articles (11/2005 - 10/2005)|
|6.||Howell, Scott K: 2 articles (11/2005 - 10/2005)|
|7.||Thornalley, Paul J: 2 articles (10/2005 - 09/2004)|
|8.||Ahmed, Naila: 2 articles (10/2005 - 09/2004)|
|9.||Hasan, Qambar: 1 article (01/2015)|
|10.||Alam, Khursheed: 1 article (01/2015)|
|1.||Diabetic Nephropathies (Diabetic Nephropathy)
11/01/2005 - "This study examines the relationship of methylglyoxal, 3-deoxyglucosone (3DG), and oxidative stress levels to diabetic nephropathy risk in three populations with diabetes. "
10/29/1993 - "The increased serum concentration of 3-deoxyglucosone in the diabetic patients suggests that 3-deoxyglucosone may be responsible for the development of diabetic complications such as diabetic nephropathy by promoting the formation of advanced glycation end products."
01/01/1996 - "To investigate a role of the Maillard reaction in the pathogenesis of diabetic nephropathy, we measured serum levels of 3-deoxyglucosone (3-DG), a potent protein cross-linking intermediate of the Maillard reaction, and tissue contents of advanced glycation end products (AGEs) in streptozotocin (STZ)-induced diabetic rats. "
|2.||Hepatocellular Carcinoma (Hepatoma)
11/01/2013 - "These studies suggest that 3-deoxyglucosone and methylglyoxal impair invasion, migration, and adhesion of hepatocellular carcinoma. "
09/15/1995 - "The viability of hepatoma cells in the presence of 3-deoxyglucosone and glyceraldehyde was decreased by an aldose reductase inhibitor, ONO-2235 (5-[1Z,2E)-2-methyl-3-phenylpropenylidene]-4-oxo-2-thioxo -3- thiazolidineacetic acid). "
09/01/2011 - "Glucose incremental area under the concentration curve significantly correlated with high-sensitivity C-reactive protein, tumour necrosis factor α, interleukin-6, methylglyoxal and 3-deoxyglucosone incremental area under the concentration curve. "
09/01/2011 - "In the sub-study, glucose, insulin, triglycerides, high-sensitivity C-reactive protein, tumour necrosis factor α, interleukin-6, methylglyoxal and 3-deoxyglucosone were measured during the post-meal period of a mixed-meal breakfast at the final visit. "
01/01/2015 - "3-deoxyglucosone (3-DG) is one of the dicarbonyl species that rapidly forms several protein-AGE complexes that are believed to be involved in the pathogenesis of several diseases, particularly diabetic complications. "
06/01/2003 - "3-Deoxyglucosone (3-DG), a highly reactive intermediate of the glycation reaction, has been suggested to contribute to the development of diabetes complications. "
08/12/1994 - "A specific assay of 3-deoxyglucosone (3-DG) was developed in our laboratory to help elucidate the relationship between advanced Maillard reaction and diabetic complications. "
01/01/2001 - "3-Deoxyglucosone (3DG) is a highly reactive alpha-dicarbonyl sugar and potent protein cross-linker that is important in the formation of advanced glycation end products (AGEs), which have been postulated to lead to the development of diabetic complications. "
01/26/1990 - "The increase in the concentration of fructose 3-phosphate in the lens of diabetic rats suggests that it and its hydrolysis product, 3-deoxyglucosone, may be responsible in part for the development of some diabetic complications in the lens."
12/12/2003 - "In hyperglycemia, production of 3-deoxyglucosone, at least in part via the polyol pathway, provides an amplification loop to sustain AGE generation, oxidant stress, and vascular activation. "
02/01/1998 - "The reaction intermediates include methylglyoxal (MG) and 3-deoxyglucosone (3-DG), both of which are cytotoxic dicarbonyl compounds and are elevated during hyperglycemia. "
12/01/1998 - "Whole embryo culture was used to investigate a possible association of hyperglycemia-induced disturbances of embryo development with tissue levels of the three alpha-oxoaldehydes: glyoxal, methylglyoxal, and 3-deoxyglucosone (3-DG). "
10/01/2005 - "Decreasing postprandial hyperglycemia with lispro gave 10-20% decreases of the major free glycation adducts, hydroimidazolones derived from methylglyoxal and 3-deoxyglucosone, and glyoxal-derived Nepsilon-carboxymethyl-lysine. "
|3.||Interleukin-6 (Interleukin 6)
|7.||Advanced Glycosylation End Products
|9.||Proteins (Proteins, Gene)