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tolmesoxide
structure
Also Known As:
4,5-dimethoxy-o-tolyl methylsulfoxide; RX 71107; 1,2-dimethoxy-4-methyl-5-(methylsulfinyl)benzene
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Sulfoxides: 23
tolmesoxide: 5
Related Diseases
1.
Heart Failure
10/01/1986 - "
This haemodynamic profile of tolmesoxide would explain the beneficial effects obtained with this drug in the treatment of cardiac failure.
"
01/01/1981 - "
Clinical pharmacology of tolmesoxide in refractory heart failure.
"
01/01/1982 - "
Haemodynamic changes in heart failure induced by a new vasodilator tolmesoxide.
"
01/01/1982 - "
Tolmesoxide is a new, direct-acting vasodilator drug for use in the management of both hypertension and cardiac failure.
"
01/01/1981 - "
The haemodynamic effects and pharmacokinetics of single intravenous doses of tolmesoxide, a new vasodilator agent, were studied in 6 patients with severe cardiac failure secondary to ischaemic cardiomyopathy and refractory to conventional therapy.
"
2.
Hypertension (High Blood Pressure)
01/01/1982 - "
The haemodynamic response and pharmacokinetics of single dose oral tolmesoxide were studied at various dose levels in 4 patients with severe hypertension.
"
01/01/1982 - "
In the treatment of inadequately controlled hypertension, tolmesoxide has a limited role as an alternative vasodilator.
"
01/01/1982 - "
Tolmesoxide is a new, direct-acting vasodilator drug for use in the management of both hypertension and cardiac failure.
"
01/01/1982 - "
The haemodynamic effect of Tolmesoxide, a new sulphoxide chemically dissimilar from other vasodilators, was investigated in eight patients with chronic heart failure subsequent to ischaemic heart disease and/or hypertension.
"
3.
Cardiomyopathies (Cardiomyopathy)
01/01/1981 - "
The haemodynamic effects and pharmacokinetics of single intravenous doses of tolmesoxide, a new vasodilator agent, were studied in 6 patients with severe cardiac failure secondary to ischaemic cardiomyopathy and refractory to conventional therapy.
"
4.
Hypotension (Low Blood Pressure)
10/01/1986 - "
Tolmesoxide administration resulted in marked systemic hypotension which was associated with myocardial stimulation (increase in heart rate and LVdP/dtmax).
"
5.
Heart Diseases (Heart Disease)
01/01/1982 - "
The haemodynamic effect of Tolmesoxide, a new sulphoxide chemically dissimilar from other vasodilators, was investigated in eight patients with chronic heart failure subsequent to ischaemic heart disease and/or hypertension.
"
Related Drugs and Biologics
1.
Vasodilator Agents (Vasodilators)
2.
sulfoxide
Related Therapies and Procedures
1.
Therapeutics