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staphylolysin

dry substance of endotoxin of Staphylococcus haemolytic

Also Known As:

alpha-staphylolysin; gamma-staphylolysin; staphylolsin

Networked: 16 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Biological Factors: 2472
- Biological Toxins: 20
  - Bacterial Toxins: 814
    - Endotoxins: 14335
      - staphylolysin: 16

Experts

1.	Barequet, Irina S: 2 articles (02/2012 - 07/2009)
2.	Kessler, Efrat: 2 articles (02/2012 - 07/2009)
3.	Ohman, Dennis E: 2 articles (02/2012 - 07/2009)
4.	Rosner, Mordechai: 2 articles (02/2012 - 07/2009)
5.	Safrin, Mary: 2 articles (02/2012 - 07/2009)
6.	Aittoniemi, J: 1 article (04/2015)
7.	Haapala, A-M: 1 article (04/2015)
8.	Huttunen, R: 1 article (04/2015)
9.	Karppelin, M: 1 article (04/2015)
10.	Kere, J: 1 article (04/2015)

Related Diseases

1.	Endophthalmitis (Ophthalmia) 07/01/2009 - "Staphylolysin is effective in the treatment of experimental MRSA-induced endophthalmitis in rats, and causes no morphological adverse effects to ocular tissues. " 07/01/2009 - "The purpose of this study was to evaluate the efficacy of staphylolysin as a therapy for experimental methicillin-resistant Staphylococcus aureus (MRSA) endophthalmitis, focusing on its bactericidal activity. " 07/01/2009 - "Evaluation of Pseudomonas aeruginosa staphylolysin (LasA protease) in the treatment of methicillin-resistant Staphylococcus aureus endophthalmitis in a rat model."
2.	Keratitis 02/01/2012 - "The purpose of the current study was to study the effect of treatment with staphylolysin on experimental keratitis caused by various Staphylococcus aureus strains. " 02/01/2012 - "Staphylolysin is an effective therapeutic agent for Staphylococcus aureus experimental keratitis." 10/01/2001 - "There were no uniform patterns of characteristics of isolates from other types of infection; however, all strains from urinary tract infections possessed the exoS gene, all strains from environment and feces and the major part of keratitis and wound isolates exhibited high elastase and alkaline protease activity, and all strains from feces showed high staphylolysin activity, indicating that these virulence factors may be important in the pathogenesis of these infectious diseases."
3.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/1967 - "[Studies on the level of anti-alpha-staphylolysin (ASTA) and anti-streptolysin O (ASO) in the course of psoriasis]."
4.	Staphylococcal Infections 01/18/1980 - "The method suggested, both easy and rapid, could be used in association with anti-staphylolysin dosage for serological diagnosis of staphylococcal infections." 05/01/1979 - "The method suggested, both easy and rapid, could be used in association with anti-staphylolysin dosage for serological diagnosis of staphylococcal infections." 02/05/1976 - "Only 45% of the patients with staphylococcal infection had a positive anti-staphylolysin titer. "
5.	Infections 02/01/2012 - "The number of bacteria in the staphylolysin-treated corneas was significantly reduced in all infections with the four S. " 07/01/2009 - "Two therapeutic regimens were evaluated: (i) an intravitreal injection of staphylolysin at 6 hours post-infection; (ii) two successive intravitreal injections of staphylolysin given at 6 and 30 hours post-infection. " 02/01/2012 - "Topical treatment with either staphylolysin or bovine serum albumin (BSA; control) was applied every half hour for 5 h, starting at 4 h after infection. " 10/01/2001 - "There were no uniform patterns of characteristics of isolates from other types of infection; however, all strains from urinary tract infections possessed the exoS gene, all strains from environment and feces and the major part of keratitis and wound isolates exhibited high elastase and alkaline protease activity, and all strains from feces showed high staphylolysin activity, indicating that these virulence factors may be important in the pathogenesis of these infectious diseases."

Related Drugs and Biologics

1.	streptolysin O
2.	Virulence Factors (Pathogenicity Factors)
3.	Antirheumatic Agents (DMARD)
4.	Bovine Serum Albumin
5.	Prednisolone (Predate)
6.	Peptide Hydrolases (Proteases)
7.	Pancreatic Elastase (Elastase)
8.	Methicillin (Metin)
9.	Aspirin (Acetylsalicylic Acid)
10.	Antibodies

Related Therapies and Procedures

1.	Therapeutics
2.	Intravitreal Injections
3.	Injections