purothionin

polypeptide of relatively low MW; toxic to vertebrates and some bacteria & yeasts; purothionin A-I is believed to be identical to beta-purothionin; RN given refers to cpd with unknown MF

Also Known As:

PUR-A1 protein, Triticum aestivum; PUR-B1protein, Triticum aestivum; alpha-purothionin; beta-purothionin; purothionin protein,

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Antimicrobial Cationic Peptides: 414
        purothionin: 8
  - Plant Proteins: 334
    - purothionin: 8
- Peptides: 82426
  - Antimicrobial Peptides: 3727
    - Antimicrobial Cationic Peptides: 414
      - purothionin: 8
  - Antimicrobial Cationic Peptides: 414
    - purothionin: 8

Experts

1.	Giavi, Stavroula: 2 articles (01/2014 - 10/2013)
2.	Mäkelä, Mika: 2 articles (01/2014 - 10/2013)
3.	Pahr, Sandra: 2 articles (01/2014 - 10/2013)
4.	Papadopoulos, Nikolaos G: 2 articles (01/2014 - 10/2013)
5.	Pelkonen, Anna: 2 articles (01/2014 - 10/2013)
6.	Valenta, Rudolf: 2 articles (01/2014 - 10/2013)
7.	Vrtala, Susanne: 2 articles (01/2014 - 10/2013)
8.	Felenda, Jennifer E: 1 article (05/2019)
9.	Stintzing, Florian C: 1 article (05/2019)
10.	Turek, Claudia: 1 article (05/2019)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 02/01/1985 - "Suppression of human melanoma growth in nude mice injected with anti high-molecular-weight melanoma-associated antigen monoclonal antibody 225.28S conjugated to purothionin." 01/01/1983 - "The toxic agent purothionin was conjugated to the monoclonal antibody 225.28S to a human high-molecular-weight melanoma-accociated antigen. "
2.	Hypersensitivity (Allergy) 01/01/2014 - "Recently, we isolated a cDNA coding for wheat alpha-purothionin which is recognized by wheat food allergic patients at risk for severe wheat-induced allergy. " 10/01/2013 - "α-Purothionin, a new wheat allergen associated with severe allergy."
3.	Carcinogenesis 09/01/2012 - "Antimutagens (β-purothionin and crown compound) as modulators of expression of genes involved in carcinogenesis in human cells."
4.	Polyploidy 08/01/1988 - "To determine whether the Triticum urartu genome is more closely related to the A or B genome of the polyploid wheats, the amino acid sequence of its purothionin was compared to the amino acid sequences of the purothionins in Triticum monococcum, Triticum turgidum, and Triticum aestivum. "
5.	Neoplasms (Cancer) 05/23/2019 - "preparations and their main constituents in comparison with ricin and purothionin on human cancer cells."

Related Drugs and Biologics

1.	Monoclonal Antibodies
2.	Complementary DNA (cDNA)
3.	Antimutagenic Agents (Antimutagens)
4.	Ricin
5.	Antigens
6.	Allergens
7.	HMW-MAA