neosolaniol

RN given refers to (3 alpha,4 beta,8 alpha)-isomer

Also Known As:

3 alpha hydroxy-4 beta,8 alpha,15-triacetoxy-12,13-epoxytrichothec-9-ene; Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,8,15-triacetate, (3alpha,4beta,8alpha)-

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Trichothecenes: 97
        neosolaniol: 8
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Trichothecenes: 97
    - neosolaniol: 8
Biological Factors: 2472
- Biological Toxins: 20
  - Mycotoxins: 1745
    - Trichothecenes: 97
      - neosolaniol: 8

Experts

1.	Wu, Wenda: 2 articles (11/2017 - 01/2017)
2.	Zhang, Haibin: 2 articles (11/2017 - 01/2017)
3.	Zhang, Jie: 2 articles (11/2017 - 01/2017)
4.	Adel Rad, Khoda Berdi: 1 article (01/2021)
5.	Barba, Francisco J: 1 article (01/2021)
6.	Berrada, Houda: 1 article (01/2021)
7.	Escrivá, Laura: 1 article (01/2021)
8.	Khoshnia, Masoud: 1 article (01/2021)
9.	Niknejad, Farhad: 1 article (01/2021)
10.	Li, Yuanyuan: 1 article (11/2017)

Related Diseases

1.	Anorexia 01/01/2017 - "Role of Peptide YY3-36 and Glucose-Dependent Insulinotropic Polypeptide in Anorexia Induction by Trichothecences T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol." 01/01/2017 - "In this study, we hypothesized that anorexia induced by type A trichothecenes, including T-2 toxin (T-2), HT-2 toxin (HT-2), diacetoxyscirpenol (DAS), and neosolaniol (NEO), in mice corresponds to the changes in the gut satiety hormones peptide YY3-36 (PYY3-36) and glucose-dependent insulinotropic polypeptide (GIP) in plasma. " 11/15/2017 - "Gut satiety hormones cholecystokinin and glucagon-like Peptide-17-36 amide mediate anorexia induction by trichothecenes T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol."
2.	Body Weight (Weight, Body) 01/01/1982 - "The corresponding daily dose was 0.24 mg T-2 toxin and 0.02 mg neosolaniol/kg body weight/day. " 04/01/1978 - "The 7-day median lethal dose values of purified 8-acetylneosolaniol, diacetoxyscirpenol, T-2 toxin, HT-2 toxin, neosolaniol, deacetyl-HT-2 toxin, and T-2 tetraol were 3.22 +/- 0.26, 3.82 +/- 0.40, 4.97 +/- 0.44, 7.22 +/- 0.39, 24.87 +/- 2.64, 30.18 +/- 7.53 (incomplete value), and 33.79 +/- 5.39 mg/kg of body weight, respectively. "
3.	Poisoning 06/01/1972 - "IV. Microbial survey on "bean-hulls poisoning of horses" with the isolation of toxic trichothecenes, neosolaniol and T-2 toxin of Fusarium solani M-1-1."
4.	Lymphoma (Lymphomas) 03/01/1989 - "Forty-two analogues and reaction products derived from T-2 toxin or neosolaniol were assayed for their cytotoxicity to cultured mouse lymphoma cells. "
5.	Herpes Zoster 06/01/2023 - "Similarly, combined DON + FUM+ T-2 + neosolaniol decreased zona-occluden transcription by 2.3 and 7.6-fold on 3 and 14 dpi, respectively (P < 0.05). "

Related Drugs and Biologics

1.	T-2 Toxin (T 2 Toxin)
2.	HT-2 toxin
3.	diacetoxyscirpenol
4.	amsonic acid (DAS)
5.	Peptide Hormones (Polypeptide Hormones)
6.	Peptides (Polypeptides)
7.	Glucose (Dextrose)
8.	Type A Trichothecenes
9.	Trichothecenes
10.	Biomarkers (Surrogate Marker)