melarsonic acid (melarsonyl potassium)

RN given refers to parent cpd

Also Known As:

melarsonyl potassium; 2-(4-(4,6-diamino-s- triazin-2-ylamino)phenyl)-1,3,2-dithiaarsolane-4,5- carboxylic acid; Mel W; Trimelarsan; melarsonic acid, dipotassium salt

Networked: 13 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chien, Shu: 2 articles (02/2007 - 09/2003)
2.	Ka, Weibo: 2 articles (02/2007 - 09/2003)
3.	Sun, Dagong: 2 articles (02/2007 - 09/2003)
4.	Wen, Zongyao: 2 articles (02/2007 - 09/2003)
5.	Yao, Weijuan: 2 articles (02/2007 - 09/2003)
6.	He, Dongqi: 1 article (02/2007)
7.	Wang, Xianwei: 1 article (02/2007)
8.	Zeng, Zhu: 1 article (02/2007)
9.	Zhang, Yingyu: 1 article (02/2007)
10.	Zhou, Shupei: 1 article (02/2007)

Related Diseases

1.	Onchocerciasis 08/31/1961 - "[Therapeutic trials of Mel W in onchocerciasis and loiasis]." 01/01/1970 - " is emphasized that the risks of arsenical encephalopathy should at present preclude the use of melarsonyl potassium in the treatment of onchocerciasis, but that if this danger could be avoided the drug might prove to be of considerable use for mass therapy in control campaigns." 10/01/1962 - "Mel W in the treatment of onchocerciasis in leprosy patients: results in 12 cases observed for 20 months after treatment." 01/01/1960 - "[2 Cases showing the therapeutic results in onchocerciasis after treatment with mel W (pentylthioarsaphenylmelamine) and TWSb (antimony dimercaptosuccinate)]." 01/01/1968 - "Suramin and Mel W are the only two drugs at present known to be effective against the adult worms of Onchocerca volvulus, but in view of the unpredictable occurrence of fatal arsenical encephalopathy in a small proportion of patients receiving Mel W, suramin remains the preferred macrofilaricide in the treatment of onchocerciasis. "
2.	Brain Diseases (Brain Disorder) 01/01/1970 - " is emphasized that the risks of arsenical encephalopathy should at present preclude the use of melarsonyl potassium in the treatment of onchocerciasis, but that if this danger could be avoided the drug might prove to be of considerable use for mass therapy in control campaigns." 01/01/1968 - "Suramin and Mel W are the only two drugs at present known to be effective against the adult worms of Onchocerca volvulus, but in view of the unpredictable occurrence of fatal arsenical encephalopathy in a small proportion of patients receiving Mel W, suramin remains the preferred macrofilaricide in the treatment of onchocerciasis. "
3.	Loiasis 08/31/1961 - "[Therapeutic trials of Mel W in onchocerciasis and loiasis]."
4.	Trypanosomiasis 01/01/1964 - "[INCIDENTS AND ACCIDENTS OF TREATMENT OF TRYPANOSOMIASIS WITH MEL W. " 11/01/1959 - "[Pentylthiarsaphenylmelamine (Mel W) in the treatment of trypanosomiasis due to T. "
5.	Intestinal Volvulus (Volvulus) 12/01/1979 - "volvulus except for melarsonyl potassium which was macrofilarticidal against O. "

Related Drugs and Biologics

1.	Suramin (Suramin Sodium)
2.	Itraconazole (Sporanox)
3.	Trimetrexate (JB11)
4.	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)
5.	Spiramycin
6.	Sulfadiazine (Sulphadiazine)
7.	Pyrimethamine (Daraprim)
8.	Proteins (Proteins, Gene)
9.	Primaquine
10.	Pentamidine (NebuPent)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Therapeutics