2,6-dichloro-4-nitrophenol

05/01/2020 - "SN38/DCNP significantly inhibit tumor growth and improved the survival rate. "
08/01/2023 - "Moreover, DCNP induced robust, and long-lived neoantigen-specific CD8+ T cell responses that significantly delayed tumor growth. "
05/01/2020 - "In vivo model, DCNP reduced the non-specific distribution of SN38 in the circulation and other tissues, while shows superior tumor targeting ability. "
05/01/2020 - "The SN38/DCNP can rapidly release the anti-tumor drug under acidic conditions. "
08/01/2023 - "Collectively, our findings indicate that DCNP is a promising platform that could improve the development of personalized therapeutic neoantigen vaccines for cancer immunotherapy."

01/01/2020 - "Collectively, these data suggest that GT DcNP could be effective against advancing metastatic breast cancer with a margin of safety. "
01/01/2020 - "As the DcNP formulation is intentionally designed to be simple, scalable, and long-acting, it may be suitable for clinical development to find effective treatment against metastatic breast cancer."
01/01/2020 - "Using 4T1 as a syngeneic model for breast cancer metastasis, we found that a single GT (20/2 mg/kg) dose in DcNP nearly eliminated colonization in the lungs. "
12/31/2021 - "The in vivo probing of GT DcNPs labeled with a near-infrared marker, indocyanine green, in mice by bio-imaging and G and T analyses indicated LFA1-P enhanced drug and GT DcNP localization in breast cancer cells. "

01/01/2020 - "Using 4T1 as a syngeneic model for breast cancer metastasis, we found that a single GT (20/2 mg/kg) dose in DcNP nearly eliminated colonization in the lungs. "

02/01/2014 - "A detrimental increase in fasting glucose, insulin, and homeostasis model assessment of insulin resistance (HOMAIR) was verified only in DCNP, while NCDP and CT groups presented a non-significant reduction. "

08/01/2020 - "Dendritic cell neurofibroma with pseudorosettes (DCNP) is a rare benign peripheral nerve sheath tumor. "
02/01/2014 - "We report cases of dendritic cell neurofibroma with pseudorosettes (DCNP) presenting in the oral cavity and discuss clinicopathologic and immunohistochemical features that differentiate this from other benign peripheral nerve sheath tumors. "