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cumene (cumol)

Also Known As:
cumol; 2-phenylpropane; isopropylbenzene
Networked: 13 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. National Toxicology Program: 2 articles (09/2013 - 02/2009)
2. Ahmadi, Abbas: 2 articles (10/2012 - 01/2012)
3. Khalili, Mohsen: 2 articles (10/2012 - 01/2012)
4. Nahri-Niknafs, Babak: 2 articles (10/2012 - 01/2012)
5. Ton, Thai-Vu T: 2 articles (07/2008 - 07/2008)
6. Sills, Robert C: 2 articles (07/2008 - 07/2008)
7. Lahousse, Stephanie A: 2 articles (07/2008 - 07/2008)
8. Wakamatsu, Nobuko: 2 articles (07/2008 - 07/2008)
9. Hong, Hue-Hua L: 2 articles (07/2008 - 07/2008)
10. Clayton, Natasha P: 2 articles (07/2008 - 07/2008)

Related Diseases

1. Carcinoma (Carcinomatosis)
2. Adenoma (Adenomas)
3. Neoplasms (Cancer)
09/01/2013 - "From this assessment, the NTP recommended that cumene be listed as reasonably anticipated to be a human carcinogen in the RoC based on sufficient evidence from studies in experimental animals, which found that cumene exposure caused lung tumors in male and female mice and liver tumors in female mice. "
09/01/2013 - "This monograph provides an assessment of the available scientific information on cumene, including human exposure and properties, disposition and toxicokinetics, cancer studies in experimental animals, and studies of mechanisms and other related effects, including relevant toxicological effects, genetic toxicology, and mechanisms of carcinogenicity. "
09/01/2013 - "In addition, mutations of the K-ras oncogene and p53 tumor-suppressor gene observed in cumene-induced lung tumors in mice, along with altered expression of many other genes, resemble molecular alterations found in human lung and other cancers. "
09/01/2013 - "The monograph consists of two components: (Part 1) the cancer evaluation, which reviews the relevant scientific information, assesses its quality, applies the RoC listing criteria to the scientific information, and provides the NTP recommendation for listing status for cumene in the RoC, and (Part 2) the substance profile proposed for the RoC, containing the NTP's listing status recommendation, a summary of the scientific evidence considered key to reaching that decision, and data on properties, use, production, exposure, and Federal regulations and guidelines to reduce exposure to cumene. "
02/01/2009 - "We studied cumene to determine if it caused cancer in rats or mice. "
4. Poisoning
5. Edema

Related Drugs and Biologics

1. cumene (cumol)
2. piperazine
3. Phosphotransferases (Kinase)
4. Histamine (Histamine Dihydrochloride)
5. Formaldehyde (Formol)
6. Hydrogen Peroxide (Hydroperoxide)
7. 2-Propanol (Isopropyl Alcohol)
8. Acetic Acid (Vinegar)
9. Biological Markers (Surrogate Marker)
10. Lutein