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O(6)-methyl-2'-deoxyguanosine

RN given refers to (beta)-isomer

Also Known As:

2'-deoxy-O(6)-methylguanosine; O(6)-methyl-2'-deoxyguanosine, (alpha)-isomer; O(6)-methyldeoxyguanosine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Guanosine: 1156
        Deoxyguanosine: 166
        O(6)-methyl-2'-deoxyguanosine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Guanosine: 1156
      - Deoxyguanosine: 166
        O(6)-methyl-2'-deoxyguanosine: 2
  - Deoxyribonucleosides: 34
    - Deoxyguanosine: 166
      - O(6)-methyl-2'-deoxyguanosine: 2

Experts

1.	Brink, Andreas: 1 article (12/2007)
2.	Lutz, Werner K: 1 article (12/2007)
3.	Schulz, Berta: 1 article (12/2007)
4.	Stopper, Helga: 1 article (12/2007)

Related Diseases

1.	Neoplasms (Cancer) 12/15/1985 - "O(6)-methyldeoxyguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer."
2.	Lymphoma (Lymphomas) 12/01/2007 - "These questions were addressed by measuring the two DNA adducts 7-methylguanine (7-mG) and O(6)-methyl-2'-deoxyguanosine (O(6)-mdGuo) by LC-MS/MS in parallel to two biological endpoints of genotoxicity (comet assay and in vitro micronucleus test), using large batches of L5178Y mouse lymphoma cells treated with methyl methanesulfonate (MMS). "

Related Drugs and Biologics

1.	DNA Adducts
2.	Methyl Methanesulfonate
3.	DNA (Deoxyribonucleic Acid)
4.	7-methylguanine