thienamycin

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38 relevant articles (5 outcomes, 2 trials/studies) found for this Bio-Agent

Description: beta-lactam antibiotic; RN given refers to cpd without isomeric designation

Also Known As:

epithienamycin; thienamycin, ((5alpha,6alpha(S*))-(+-))-isomer; thienamycin, (5R-(5alpha,6alpha(R*)))-isomer; thienamycin, (5R-(5alpha,6alpha(S*)))-isomer; thienamycin, (5R-(5alpha,6beta(S*)))-isomer; tienamycin; 1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((2-aminoethyl)thio)-6-(1-hydroxyethyl)-7-oxo-,

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 42

Polycyclic Compounds: 59

Bridged Compounds: 3

Bicyclo Compounds

Heterocyclic Bicyclo Compounds

Related Diseases

1.	Infection 01/01/1991 - "Tienamycin was administered 24 hours, 2 hours prior the infection and 2 hours after the infection (model I), 24 hours and 48 hours after infecting the mice (model II). " 03/01/1986 - "aeruginosa infections, thienamycin or another antipseudomonal beta-lactam should be combined with an aminoglycoside." 01/01/1983 - "The antibacterial activity of N-formimidoyl-thienamycin was tested by means of the infection- and therapy model of the acute, occlusive pyelonephritis in rats. " 01/01/1991 - "Thienamycin, which is rather labile, has been transformed into a more stable product, imipenem, which is used in the treatment of infections with gram-positive and -negative bacteria. " 03/01/1986 - "Thienamycin is the most promising of the new beta-lactams for single-agent therapy of severe infections but may also be associated with the emergence of resistant P. " Order ALL the reference details at left...
2.	Respiratory Tract Infections (Respiratory Tract Infection) 09/01/1982 - "Our data suggest that N-formimidoyl thienamycin may have therapeutic efficacy against respiratory infections with P. " 01/01/1996 - "[Selected immune response parameters in respiratory tract infections in mice--effect of combined treatment with tienamycin and coparvax]" Order ALL the reference details at left...
3.	Pyelonephritis 02/01/1984 - "Treatment of staphylococcal pyelonephritis in rats with N-formimidoyl thienamycin." 01/01/1983 - "The antibacterial activity of N-formimidoyl-thienamycin was tested by means of the infection- and therapy model of the acute, occlusive pyelonephritis in rats. " 02/01/1984 - "The therapeutic efficacy of N-formimidoyl thienamycin alone or coadministered with MK0791, an inhibitor of renal dehydropeptidase-I, compared to methicillin in experimental pyelonephritis in rats was investigated. " Order ALL the reference details at left...
4.	Escherichia coli Meningitis 03/01/1982 - "Pharmacokinetics and bacteriological efficacy of N-formimidoyl thienamycin in experimental Escherichia coli meningitis." Order ALL the reference details at left...
5.	Sepsis (Septicemia) 01/01/1984 - "This experimental model was used to evaluate the efficacy of benzylpenicillin, benzylpenicillin plus sulbactam, cefoxitin, thienamycin, clindamycin, tinidazole, netilmicin, clindamycin plus netilmicin, and tinidazole plus netilmicin in the treatment of intraabdominal sepsis. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Cefoxitin (Cefoxitin Sodium)
2.	Cilastatin
3.	Clindamycin (Cleocin)
4.	Tobramycin (Nebcin)
5.	dipeptidase (membrane dipeptidase)
6.	Penicillin G (Benzylpenicillin)
7.	Tinidazole
8.	Sulbactam
9.	Netilmicin (Netromycin)
10.	Methicillin (Metin)

Related Therapies and Procedures

1.	Chemoprevention
2.	Intensive Care (Surgical Intensive Care)
3.	Drug Therapy (Chemotherapy)

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