|1.||Inaba, Masaaki: 7 articles (02/2006 - 10/2002)|
|2.||Nishizawa, Yoshiki: 7 articles (02/2006 - 10/2002)|
|3.||Ishimura, Eiji: 7 articles (02/2006 - 10/2002)|
|4.||Okuno, Senji: 6 articles (02/2006 - 10/2002)|
|5.||Fraser, W D: 6 articles (12/2005 - 09/2000)|
|6.||Yamakawa, Tomoyuki: 5 articles (02/2006 - 05/2005)|
|7.||Sato, Y: 5 articles (08/2001 - 04/2000)|
|8.||Delmas, P D: 4 articles (07/2006 - 01/2000)|
|9.||Garnero, P: 4 articles (07/2006 - 06/2001)|
|10.||Ueda, Misako: 4 articles (02/2006 - 10/2002)|
11/01/1992 - "The method shows considerable promise as a rapid and specific index of human bone resorption rates, with greatly improved specificity and convenience over total pyridinoline analysis. "
11/24/2000 - "Femur weights and serum concentrations of pyridinoline, a reliable marker of bone resorption, were measured at the end of the study period. "
09/01/2013 - "The nonadherent population of BMSCs harvested from the long bone diaphysis of KO animals formed more osteoclasts, a finding that was associated with increased circulatory levels of pyridinoline, a marker of bone resorption. "
10/01/2011 - "In conclusion, the pyridinoline test was not proper for bone resorption even pyridinoline was abundant in bone."
08/01/2002 - "Bone resorption was assessed by measuring the urinary concentrations of pyridinoline and deoxypiridinoline. "
|2.||Prostatic Neoplasms (Prostate Cancer)
02/01/1997 - "Pyridinoline cross-linked carboxyterminal telopeptide might assist PSA and bone scintigraphy in monitoring metastatic bone activity of prostatic cancer."
08/01/1998 - "Also, urinary pyridinoline and deoxypyridinoline were compared in 2 groups of patients with metastatic prostate cancer of the bone who demonstrated progression or positive response to treatment. "
11/01/1996 - "Also, urinary pyridinoline and deoxypyridinoline were compared in 2 groups of patients with metastatic prostate cancer of the bone who demonstrated progression or positive response to treatment. "
09/01/2001 - "Pyridinoline cross-linked carboxyterminal telopeptide of type I collagen as a useful marker for monitoring metastatic bone activity in men with prostate cancer."
08/01/1998 - "Measurement of urinary pyridinoline and deoxypyridinoline may provide a useful marker of prostate cancer metastatic to bone and may be useful in monitoring the response to treatment."
|3.||Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
08/01/1998 - "Levels of urinary pyridinoline and deoxypyridinoline in urine in patients with bony metastatic prostate cancer were significantly greater than levels in patients with benign prostatic hyperplasia or localized prostate cancer. "
04/01/1994 - "Urinary excretion of pyridinoline and deoxypyridinoline was significantly greater in patients with metastatic carcinoma of the prostate compared with patients with either benign prostatic hyperplasia (Mann-Whitney-Wilcoxon rank sum analysis, p < 0.00004 and 0.002, respectively) or localized prostate cancer (Mann-Whitney-Wilcoxon, p < 0.00001 and 0.00005, respectively). "
08/01/1998 - "Urinary pyridinoline and deoxypyridinoline were measured in patients with benign prostatic hyperplasia, clinically localized prostate cancer and prostate cancer with bone metastases. "
11/01/1996 - "Levels of pyridinoline and deoxypyridinoline in urine, and the level of alkaline phosphatase in serum from patients with bone metastatic prostate cancer were significantly greater than levels in patients with benign prostatic hyperplasia or localized prostate cancer. "
11/01/1997 - "Serum concentrations of the carboxyterminal propeptide of Type I procollagen (PICP), the carboxyterminal pyridinoline cross-linked telopeptide of Type I collagen (ICTP), and prostate specific antigen (PSA) were measured by radioimmunoassays in 48 patients with benign prostatic hyperplasia (BPH), 25 patients with prostate carcinoma (PCA) without bone metastases, and 36 patients with PCA and bone metastases. "
|4.||Neoplasm Metastasis (Metastasis)
02/01/1997 - "Pyridinoline cross-linked carboxyterminal telopeptide, an osteoclastic marker, reflected the extent of bone metastasis more accurately than PSA and other bone markers. "
07/01/1996 - "The aim of this study was to evaluate the urinary pyridinium crosslink levels in breast cancer with or without osseous involvement, and to correlate it with serial doses of CA 15-3. 285 breast cancer patients (226 free of disease and 59 with bone metastases) were measured for both pyridinoline and CA 15-3. In the metastatic patients the mean values of the two markers were significantly higher than in non evident disease patients (P = < 0.01 and p = < 0.001 respectively). "
07/01/1996 - "Abnormal values over the normal were found in 22% for pyridinoline and 11% for CA 15-3 in patients free of disease while the normal values observed in patients with bone metastases were 22% for pyridinoline and 39% for CA 15-3. Tandem dosage of CA 15-3, was highly sensitive but site-aspecific, and pyridinoline, which is bone specific, may be useful chiefly in the monitoring of breast cancer treatment, since many physiological conditions such as age, menopausal status and variation over 24 hours, and cost effectiveness will influence the use of pyridinoline during follow-up."
01/01/2003 - "The efficacy of a serum carboxyterminal pyridinoline cross-linked telopeptide of type I collagen as a quantitative screening marker for bone metastases in patients with urological malignancies."
12/01/1997 - "Levels of urine pyridinoline (U-Pyr) excretion and serum carboxy-terminal propeptide of type 1 procollagen (P1CP) in patients with bone metastasis were significantly higher than those in patients without bone metastasis (P < 0.05). "
10/01/2011 - "This research studied the validity and correlation of beta-CTx (Betacrosslap) and Pyridinoline (PYD) in 71 cases of postmenopausal Thai women who attended at the osteoporosis clinic. "
07/15/2001 - "The low sensitivity indicates that the measurement of pyridinoline and desoxypyridinoline is less suitable for screening purposes, but may be useful in confirming presence or extent of osteoporosis."
07/15/2001 - "In a sample of 370 individuals recruited at random within a population survey of vertebral osteoporosis, urinary concentration of total pyridinoline and desoxypyridinoline were determined by HPLC. "
01/01/2001 - "Radiographical findings of spines and laboratory examinations including measurement of deoxy-pyridinoline are important to diagnose osteoporosis."
06/01/1999 - "The development of the urinary pyridinoline cross-link assays which measure mature bone breakdown products have been shown to be highly sensitive and specific as a measure of bone change in osteoporosis. "
|3.||Collagen Type I (Type I Collagen)
|5.||Biological Markers (Surrogate Marker)
|8.||Hydroxyproline (4 Hydroxyproline)
|1.||Hormone Replacement Therapy (Therapy, Hormone Replacement)
|4.||Continuous Ambulatory Peritoneal Dialysis (CAPD)
|5.||Coronary Artery Bypass (Coronary Artery Bypass Surgery)