Lys(8)- oxytocin (OXL)

01/08/2018 - "Consistently, OXL/TLNP induced a remarkable apoptosis of cancer cells. "
09/01/1997 - "However, OXL markedly enhanced the immunological responses of spleen cells from mice bearing hepatoma-22 tumor. "
07/20/2019 - "Importantly, OXmi-HMSN caused conspicuous inhibition of tumor growth and was significantly greater than that of either OXL or OXL-MSN (p < 0.0001). "
01/01/1991 - "Oxalysine (OXL) is a new antibiotic and shown to be effective against tumor metastatis. "
12/01/2023 - "Oxaliplatin (OXL) is a significant therapy agent for the worldwide increase in cancer cases. "

01/01/2014 - "Peripheral neuropathy is a well-recognized dose-limiting toxicity of OXL. "
06/01/2008 - "OXL induces two types of peripheral neuropathy; acute and chronic. "
06/01/2008 - "Peripheral neuropathy is a well recognized toxicity of OXL, usually resulting in dose modification. "
01/01/2021 - "Oxidative stress and mitochondrial dysfunction are key factors contributing to the development of OXL-induced peripheral neuropathy (OIPN). "
09/01/2022 - "Herein, we used the rat model of OXL-induced peripheral neuropathy to demonstrate the protective effects of naringin (NRG) in this neuropathy. "

07/20/2019 - "Our study, for the first time, proved that miRNA-204-5p can generate a synergistic anticancer effect with OXL with HMSN, and thus improve the effects of therapeutic efficacy in colon cancers. "
01/08/2018 - "The presence of TPGS remarkably increased the anticancer effect of OXL in HT-29 colon cancer cells. "
01/08/2018 - "The main aim of present study was to prepare the oxaliplatin (OXL)-loaded D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS)-based lipid nanoparticles to enhance the anticancer effect in colon cancer cells. "

07/20/2019 - "OXmi-HMSN showed 30% of TUNEL positive cells compared to 8% TUNEL positive cells for free OXL and 6% for free miRNA-204-5p treated group indicating the wide spread apoptosis of cells throughout the tissue section. "
07/20/2019 - "Importantly, OXmi-HMSN caused conspicuous inhibition of tumor growth and was significantly greater than that of either OXL or OXL-MSN (p < 0.0001). "
07/20/2019 - "Our study, for the first time, proved that miRNA-204-5p can generate a synergistic anticancer effect with OXL with HMSN, and thus improve the effects of therapeutic efficacy in colon cancers. "

01/01/2013 - "Fifteen patients (four women; 11 men; mean age, 60.1 ± 10.6 years; median, 62; range, 37-75) with colorectal cancer treated with OXL-based treatment have been clinically and neurophysiologically evaluated before and after OXL therapy. "
06/01/2008 - "Oxaliplatin (OXL) is a third-generation organoplatinum compound with significant activity mainly against colorectal cancer (CRC). "
12/01/2020 - "Colorectal carcinoma (CRC) is widely treated by chemotherapy based on an intensely neurotoxic drug: oxaliplatin (OXL). "
01/01/2022 - "The first-line anticancer agent oxaliplatin (OXL) is the preferred drug for treating colorectal cancer (CRC); however, the development of drug resistance is common in patients treated with OXL, which considerably reduces the efficacy of OXL-based regimens. "