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4-chloro-1,2-diaminobenzene
RN given refers to parent cpd
Also Known As:
4-chloro-1,2-diaminobenzene sulfate (1:1); 4-chloro-o-phenylenediamine
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Polyamines: 3918
Diamines: 518
Phenylenediamines: 6
4-chloro-1,2-diaminobenzene: 4
Aniline Compounds: 46
Phenylenediamines: 6
4-chloro-1,2-diaminobenzene: 4
Related Diseases
1.
Carcinogenesis
09/01/1992 - "
Combined administration of the carcinogens, o-anisidine, p-cresidine, and 4-chloro-o-phenylenediamine at low doses also enhanced BBN-initiated bladder carcinogenesis.
"
2.
Papilloma (Papillomatosis)
06/01/1980 - "
In both male and female Fischer rats, feeding 4-chloro-o-phenylenediamine at 0.5 or 1% in the diet led to a significant increase in hyperplasia, papilloma and carcinoma of the urinary bladder.
"
3.
Neoplasms (Cancer)
01/01/1978 - "
It is concluded that under the conditions of this bioassay 4-chloro-o-phenylenediamine was carcinogenic in Fischer 344 rats and B6C3F1 mice, inducing tumors of the urinary bladder and forestomach in both sexes of rats and hepatocellular carcinomas in both sexes of mice.
"
4.
Hyperplasia
06/01/1980 - "
In both male and female Fischer rats, feeding 4-chloro-o-phenylenediamine at 0.5 or 1% in the diet led to a significant increase in hyperplasia, papilloma and carcinoma of the urinary bladder.
"
5.
Hepatocellular Carcinoma (Hepatoma)
01/01/1978 - "
It is concluded that under the conditions of this bioassay 4-chloro-o-phenylenediamine was carcinogenic in Fischer 344 rats and B6C3F1 mice, inducing tumors of the urinary bladder and forestomach in both sexes of rats and hepatocellular carcinomas in both sexes of mice.
"
Related Drugs and Biologics
1.
Carcinogens
2.
cresidine
3.
1,2-diamino-4-nitrobenzene
4.
2-anisidine (o-anisidine)