isoxepac

orally effective non-steroidal anti-inflammatory agent with moderate analgesic & antipyretic activity; structure in first three sources

Also Known As:

HP 549; 6,11-dihydro-11-oxodibenz(b,e)oxepin-2-acetic acid

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

1.	Pain (Aches) 02/01/1982 - "Analgesic effect of isoxepac on postmeniscectomy pain: a controlled trial." 02/01/1982 - "Peak and duration of pain relief was of the same order with 50 mg indomethacin, and 200 mg isoxepac would appear to be the minimal effective dose in the clinical setting of postoperative pain following knee meniscectomy. "
2.	Postoperative Pain 02/01/1982 - "Peak and duration of pain relief was of the same order with 50 mg indomethacin, and 200 mg isoxepac would appear to be the minimal effective dose in the clinical setting of postoperative pain following knee meniscectomy. "
3.	Edema (Dropsy) 05/01/1977 - "HP 549 also inhibits carrageenan-induced paw edema in the rat, an activity which is not altered by adrenalectomy. "
4.	Dysmenorrhea (Menstrual Pain) 01/01/1980 - "Relief of menstrual discomfort and dysmenorrhea and simultaneous suppression of uterine activity by isoxepac."
5.	Rheumatoid Arthritis 02/01/1981 - "Isoxepac in rheumatoid arthritis: a double-blind comparison with aspirin." 02/01/1981 - "Nineteen patients with rheumatoid arthritis entered a double-blind cross-over study, comparing a new anti-inflammatory agent isoxepac, 200 mg three times daily, with aspirin 1.2 g three times daily. "

1.	Analgesics (Analgesic Drugs)
2.	Indomethacin (Indometacin)
3.	Carrageenan
4.	Aspirin (Acetylsalicylic Acid)
5.	Anti-Inflammatory Agents (Anti-Inflammatories)