|1.||Cunningham, Madeleine W: 3 articles (10/2005 - 01/2002)|
|2.||Kalil, Jorge: 2 articles (02/2007 - 02/2006)|
|3.||Guilherme, Luiza: 2 articles (02/2007 - 02/2006)|
|4.||Cunningham, M W: 2 articles (06/2001 - 12/2000)|
|5.||Fischetti, V A: 2 articles (06/2001 - 12/2000)|
|6.||Narula, Jagat: 1 article (03/2013)|
|7.||Sharma, Meenakshi: 1 article (03/2013)|
|8.||Kotb, Malak: 1 article (03/2013)|
|9.||Yacoub, Magdi H: 1 article (03/2013)|
|10.||Tandon, Rajendra: 1 article (03/2013)|
|1.||Rheumatic Fever (Acute Articular Rheumatism)
06/01/2001 - "In this study, we investigated the hypothesis that streptococcal M protein could produce inflammatory valvular heart lesions similar to those seen in rheumatic fever (RF). "
02/15/2006 - "Temporal changes in streptococcal M protein types and the near-disappearance of acute rheumatic fever in the United States."
09/01/1998 - "The class I epitope of streptococcal M protein is an epidemiological marker for acute rheumatic fever (ARF)-associated serotypes of group A streptococci and is recognized by anti-M protein monoclonal antibody (MAb) 10B6. "
02/01/1996 - "To analyze the immune response to the C region of group A streptococcal M protein in patients with rheumatic fever (RF), we cloned the structural gene for the C region of type 12 M protein and produced recombinant C region of M protein. "
01/01/1989 - "Evidence for two distinct classes of streptococcal M protein and their relationship to rheumatic fever."
|2.||Rheumatic Heart Disease (Rheumatic Heart Diseases)
06/01/2011 - "The purpose of this study was to determine the role of streptococcal M protein in naturally-occurring CD4(+)CD25(+) regulatory T cells (nTregs) function and development in rheumatic heart disease in Iraqi patients. "
06/01/2011 - "Functional and Developmental Analysis of CD4(+)CD25(+) Regulatory T Cells under the Influence of Streptococcal M Protein in Rheumatic Heart Disease."
02/01/2004 - "In rheumatic heart disease, streptococcal M protein specific T cells migrate to valves. "
10/15/2005 - "Mimicry between streptococcal M protein and cardiac myosin is important in the pathogenesis of rheumatic heart disease. "
03/01/2005 - "How an autoimmune reaction triggered by molecular mimicry between streptococcal M protein and cardiac tissue proteins leads to heart lesions in rheumatic heart disease."
02/01/1983 - "Studies on the pathogenesis of rheumatic carditis--cytotoxicity of serum and lymphocytes sensitized to streptococcal M protein fraction on cultured myocardial cells."
06/01/2001 - "Fifty percent (3 of 6) of Lewis rats immunized with recombinant type 6 streptococcal M protein (rM6) developed valvulitis as well as focal lesions of myocarditis. "
02/01/2004 - "By investigating streptococcal M protein and cardiac myosin in the Lewis rat model of myocarditis and valvulitis, T cell mimicry is supported as a potential mechanism in disease. "
05/01/1996 - "Streptococcal M protein peptide with similarity to myosin induces CD4+ T cell-dependent myocarditis in MRL/++ mice and induces partial tolerance against coxsakieviral myocarditis."
02/01/2004 - "In coxsackieviral myocarditis in the MRL mouse strain, cardiac myosin mimicking M protein peptide NT4 was found to induce tolerance and prevent coxsackieviral induced myocarditis, suggesting T cell mimicry between coxsackievirus and streptococcal M protein, both of which are associated with inflammatory heart disease. "
|4.||Heart Valve Diseases (Valvular Heart Disease)
06/01/2001 - "The study demonstrates that the Lewis rat is a model of valvular heart disease and that streptococcal M protein can induce an autoimmune cell-mediated immune attack on the heart valve in an animal model. "
06/01/2001 - "Induction of autoimmune valvular heart disease by recombinant streptococcal m protein."
10/01/2007 - "Immune responses against cardiac myosin lead to valvular heart disease and infiltration of the heart by Streptococcal M protein reactive T lymphocytes. "
01/01/2002 - "These data show direct evidence that immune responses against cardiac myosin lead to valvular heart disease and the infiltration of the heart by streptococcal M protein reactive T lymphocytes."
|5.||Autoimmune Diseases (Autoimmune Disease)
10/15/2005 - "The study of human T cell clones from rheumatic heart disease revealed potential sites of T cell mimicry between streptococcal M protein and human cardiac myosin and represents some of the most well-defined T cell mimicry in human autoimmune disease."
09/01/1990 - "Understanding these events may also explain the pathogenesis of autoimmune diseases associated with certain superantigens, such as streptococcal M protein that is thought to be involved in rheumatic fever and rheumatic heart disease."
01/01/1995 - "These include autoimmune diseases seen after group A streptococcal infections in which the streptococcal M protein has been postulated to act as a superantigen such as scarlet fever, rheumatic heart disease, and poststreptococcal glomerulonephritis. "
|7.||Proteins (Proteins, Gene)
|10.||Immunoglobulin G (IgG)