N-isopropyl-N-phenyl-4-phenylenediamine (IPPD)

RN given refers to parent cpd; structure in sixth source

Also Known As:

IPPD; N-isopropyl-N'-phenyl-1,4-phenylenediamine; N-isopropyl-N'-phenyl-p-phenylenediamine; N-isopropyl-N-phenyl-4-phenylenediamine hydrochloride; p-isopropylaminodiphenylamine; phenylisopropyl-p-phenylenediamine; N-(1-methylethyl)-N'-phenyl-1,4-benzenediamine

Networked: 24 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Diamines: 518
      - Phenylenediamines: 6
        N-isopropyl-N-phenyl-4-phenylenediamine: 24
  - Aniline Compounds: 46
    - Phenylenediamines: 6
      - N-isopropyl-N-phenyl-4-phenylenediamine: 24

Experts

1.	Chen, Daqing: 1 article (07/2022)
2.	Duan, Xinbin: 1 article (07/2022)
3.	Gao, Lei: 1 article (07/2022)
4.	Liu, Chunsheng: 1 article (07/2022)
5.	Peng, Weijuan: 1 article (07/2022)
6.	Zhong, Liqiao: 1 article (07/2022)
7.	Bacharewicz-Szczerbicka, Joanna: 1 article (01/2021)
8.	Cohen, Omer: 1 article (01/2021)
9.	Flisiak, Iwona: 1 article (01/2021)
10.	Gabay, Eran: 1 article (01/2021)

Related Diseases

1.	Contact Dermatitis (Eczema, Contact) 07/01/2020 - "Purpuric contact dermatitis caused by N-isopropyl-N'-phenyl-p-phenylenediamine from a Samsung Fit strap." 10/01/1996 - "N-containing antioxidants, such as IPPD, DMBPPD and ETMDQ, were thus considered as the main causative agents and the trial product was found useful for managing contact dermatitis. " 03/01/1982 - "A tire assembler developed contact dermatitis from IPPD, a rubber antioxidant. " 02/01/1977 - "Forty-two cases of contact sensitivity to N-isopropyl-N'-phenylparaphenylenediamine (IPPD), an amine antiozonant used in rubber manufacture, were collated from several firms and plants dealing with tyres. "
2.	Hypersensitivity (Allergy) 01/01/2007 - "In the group of patients (36 subjects) with IPPD allergy as many as 27 (75%) presented positive reactions. " 08/01/1987 - "IPPD contact allergy from an orthopedic bandage." 01/01/1980 - "[Contact allergy to N-isopropyl N'-phenylparaphenylenediamine (IPPD) in different individual protective devices (author's transl)]." 01/01/2021 - "Hypersensitivity to PPDA was diagnosed in 77.1%, to IPPD in 20.5%, to TDA in 6%, to TETA in 1.2%, and to EDA in 0.6% of cases. " 11/01/2001 - "Contact allergy to IPPD and diphenylthiourea in an orthopaedic brace."
3.	Allergic Contact Dermatitis 05/01/1979 - "Allergic contact dermatitis to isopropylaminodiphenylamine (IPPD)." 01/01/1977 - "Out of a total of 56 cases of allergic contact dermatitis to IPPD, 42 were considered as caused by occupational contacts: 17 cases were found in tyre manufacturers, 9 in car-mechanics, 9 in drivers, and 7 in various industrial branches. " 01/01/1977 - "Allergic contact dermatitis to N-isopropyl-N'-phenylparaphenylenediamine (IPPD) from rubber is far from being exceptional. " 01/01/2023 - "N-isopropyl-N'-phenylenediamine (IPPD): An unusual case of professional facial allergic contact dermatitis." 07/01/2011 - "In conclusion, this was an unusual pediatric case of non-occupational allergic contact dermatitis from N-isopropyl-N-phenyl-4-phenylenediamine in black rubber bicycle handgrips. "
4.	Dermatitis 04/01/1988 - "A case of allergic isopropyl-p-phenylenediamine (IPPD) dermatitis from a watch strap." 06/01/1977 - "An outbreak of rubber fingerstall dermatitis in a Danish post office was found to be caused by minute amounts of isopropylphenyl-para-phenylenediamine (IPPD) in the fingerstalls. " 12/01/2020 - "Sensitization to p-phenylenediamine, thiuram mix, and N-isopropyl-N'-phenyl-p-phenylenediamine was significantly associated with hairdressing and with hand/forearms dermatitis. " 10/01/1996 - "The following results were obtained: (i) in the patch tests, all 9 patients showed positive reactions to 1 or more of the nitrogen(N)-containing antioxidants (IPPD, DMBPPD, ETMDQ); (ii) ETMDQ was detected in 1 pair of rubber boots, and IPPD and DMBPPD in another pair; (iii) no patient using hypoallergenic boots during rice-planting had recurrent dermatitis. "
5.	Parkinson Disease (Parkinson's Disease) 10/01/2004 - "Young onset Parkinson's disease (YOPD) is defined as idiopathic Parkinson's disease (IPPD) occurring in people between 21 and 40 years of age; it strikes approximately 5% of Parkinson's patients. "

Related Drugs and Biologics

1.	Antioxidants
2.	4-phenylenediamine (p-phenylenediamine)
3.	black rubber
4.	Therapeutic Uses
5.	Thiram
6.	Nitrogen
7.	Amines
8.	3-nitro-o-phenylenediamine
9.	4-(2'-pyridyldithio)benzyldiazoacetate (PPDA)
10.	10-thiirane-4-estrene-3,17-dione

Related Therapies and Procedures

1.	Therapeutics
2.	Protective Devices (Safety Device)
3.	Braces
4.	Bandages (Bandage)