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3 beta-hydroxy-delta 5-cholenic acid
RN given refers to parent cpd
Also Known As:
3 beta-hydroxy-5-cholenic acid; 3 beta-hydroxy-5-cholenoic acid; 3 beta-hydroxy-delta 5-cholenic acid, sodium salt; 3beta-hydroxy-delta5-cholenic acid; 3 beta-hydroxychol-5-en-24-oic acid
Networked:
10
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Bile Acids and Salts: 11432
Cholic Acids: 14
3 beta-hydroxy-delta 5-cholenic acid: 10
Cholanes
Cholic Acids: 14
3 beta-hydroxy-delta 5-cholenic acid: 10
Related Diseases
1.
Obstructive Jaundice (Cholestatic Jaundice)
01/01/1982 - "
In the older children and adults with obstructive jaundice (n=6), 3 beta-hydroxy-5-cholenoic acid was excreted at a mean rate of 3.9% of total urinary bile acids, ranging from 0.63 to 14.81 mol per day.
"
06/01/1985 - "
Mean concentrations of total 3 beta-hydroxy-5-cholenoic acid in serum (mumole/liter) were as follows: Control subjects (14), 0.184; obstructive jaundice (15), 6.783; liver cirrhosis, compensated (12), 0.433, and decompensated (12), 1.636; chronic hepatitis (12), 0.241; and acute hepatitis (11), 2.364.
"
2.
Digestive System Diseases
12/01/1986 - "
Serum 3 beta-hydroxy-5-cholenoic acid (3 beta-OH-delta 5) was analyzed in 100 cases (90 patients with hepatobiliary diseases, 10 normal subjects) and its clinical significance investigated.
"
12/01/1986 - "
Clinical evaluation of serum 3 beta-hydroxy-5-cholenoic acid in hepatobiliary diseases.
"
06/01/1985 - "
3 beta-Hydroxy-5-cholenoic acid in the serum of control subjects and 62 patients with various hepatobiliary diseases was quantitated by mass fragmentography after separation into nonglucuronidated-nonsulfated, glucuronidated, and sulfated fractions.
"
06/01/1985 - "
Determination of 3 beta-hydroxy-5-cholenoic acid in serum of hepatobiliary diseases--its glucuronidated and sulfated conjugates.
"
3.
Biliary Atresia
01/01/1982 - "
In the biliary atresia group, 3 beta-hydroxy-5-cholenoic acid excreted was 0.45+/-0.28 mumol per day (n=7), and in the neonatal hepatitis group, 0.48+/-0.44 mumol per day (n=9).
"
10/01/1989 - "
The last is the detection of unusual bile acids, such as 3 beta-hydroxy-5-cholenoic acid is useful for the marker of hepatic cell carcinoma and the screening of congenital biliary atresia.
"
01/01/1982 - "
The mean rate of 3 beta-hydroxy-5-cholenoic acid to total urinary bile acids in the biliary atresia group was 2.1%, and 1.3% in the neonatal hepatitis group.
"
4.
Alagille Syndrome (Alagille-Watson Syndrome)
02/15/1985 - "
The large amounts of 3 beta-hydroxy-5-cholenoic acid measured in children with the syndrome of hepatic ductular hypoplasia could indicate the existence of an alternative fetal pathway of bile acid synthesis.
"
5.
Liver Diseases (Liver Disease)
08/01/1989 - "
Concurrent occurrence of 3 beta,12 alpha-dihydroxy-5-cholenoic acid associated with 3 beta-hydroxy-5-cholenoic acid and their preferential urinary excretion in liver diseases.
"
Related Drugs and Biologics
1.
Bile Acids and Salts (Bile Acids)
2.
Chenodeoxycholic Acid (Chenix)
3.
Cholic Acid
4.
Lithocholic Acid
5.
Acids
6.
cholest-5-en-3 beta,7 alpha-diol
7.
cholest-5-ene-3 beta,26-diol