toxic product which was generated in Italy due to an explosion in a plant manufacturing 2,4,5-trichlorophenol
Also Known As:
Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results


1. Matthews, Jason: 1 article (07/2011)
2. Powis, Melanie: 1 article (07/2011)
3. Celius, Trine: 1 article (07/2011)
4. Safe, Stephen: 1 article (03/2008)
5. Rowlands, Craig: 1 article (03/2008)
6. Zhang, Shu: 1 article (03/2008)

Related Diseases

1. Hepatocellular Carcinoma (Hepatoma)
05/15/1996 - "In this study, the ability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,7,8-tetrachlorodibenzofuran (TCDF), and selected chlorobiphenyl congeners to cause uroporphyria was examined in a fish hepatoma cell line (PLHC-1) that expresses aryl hydrocarbon (Ah) receptors and an inducible cytochrome P4501A (CYP1A). "
11/01/1996 - "2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), 2,3,7,8-tetrachlorodibenzofuran (TCDF), and benz[a]anthracene (BA) highly induce cytochrome P4501A1, determined by aryl hydrocarbon hydroxylase (AHH) activity, in human hepatoma HepG2 cells within 24 h. "
03/01/2008 - "TCDD, 1,2,3,7,8-pentachlorodibenzo-p-dioxin (PeCDD), 2,3,7,8-tetrachlorodibenzofuran (TCDF), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF), and 3,3',4,4',5-pentachlorobiphenyl (PCB126) induced CYP1A1-dependent activities in HEK293 human embryonic kidney, Panc1 pancreatic cancer, and Hepa1c1c7 mouse hepatoma cell lines. "
08/01/1989 - "Treatment of rat hepatoma H-4-IIE cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,7,8-tetrachlorodibenzofuran (TCDF), 1,2,3,7,8-pentachlorodibenzo-p-dioxin (PeCDD), 1,2,3,7,8-pentachlorodibenzofuran (PeCDF), 1,2,7,8-TCDF, and 2,3,7-trichlorodibenzo-p-dioxin (TrCDD) resulted in the structure-dependent induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase activities. "
02/01/1991 - "We have now investigated the presence of both the 4 S PAH-binding protein and the 8 S Ah receptor in rat hepatoma H4-II-E cells as well as the induction of P450IA1 upon their exposure to PAH's such as benzo[a]pyrene (BP) and 3-methylcholanthrene (3MC), and halogenated dioxins such as 2,3,7,8-tetrachlordibenzo-p-dioxin (TCDD) and 2,3,7,8-tetrachlorodibenzofuran (TCDBF). "
2. Breast Neoplasms (Breast Cancer)
3. Pancreatic Neoplasms (Pancreatic Cancer)
4. Cleft Palate (Palate, Cleft)
5. Body Weight (Weight, Body)

Related Drugs and Biologics

1. Tetrachlorodibenzodioxin (TCDD)
2. Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
3. Cytochromes
4. Cytochrome P-450 CYP1A1 (CYP1A1)
5. 1,2,3,7,8-pentachlorodibenzo-p-dioxin
6. Methylcholanthrene
7. Insulin (Novolin)
8. Dioxins
9. Carrier Proteins (Binding Protein)
10. Benzo(a)pyrene