2-propyl-2-pentenoic acid

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3 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: valproate metabolite; RN given refers to parent cpd

Also Known As:

(E)-2-ene valproic acid; 2-enVPA; 2-envalproic acid; 2-n-propylpent-2-enoic acid; 2-propyl-2-pentenoic acid, (E)-isomer; 2-propyl-2-pentenoic acid, (Z)-isomer; 2-propyl-2-pentenoic acid, sodium salt; E-delta(2)-valproic acid; delta2,3 VPE; delta2-valproic acid; trans-2-en-VPA; trans-2-en-valproate; trans-2-ene-valproic acid

Bio-Agent Context: Research Results

Lipids: 13336

Fatty Acids: 4673

Unsaturated Fatty Acids: 2227

Monounsaturated Fatty Acids: 150

2-propyl-2-pentenoic acid: 3

Related Diseases

1.	Seizures (Seizure) 02/01/1992 - "The anticonvulsant potency of trans-2-en-VPA appeared to be higher than that of VPA, especially in the case of secondarily generalized seizures" 02/01/1992 - "As in the case of VPA, trans-2-en-VPA exerted potent anticonvulsant effects against partial seizures and secondarily generalized clonic seizures in amygdala-kindled rats after i.p" 09/01/1991 - "The data show that trans-2-en-VPA exerts anticonvulsant effects against different seizure types, i.e., myoclonic, clonic, and tonic seizures in rodents and (myo)clonic seizures in dogs" 02/01/1992 - "However, as previously reported for effects of valproate in the kindling model, trans-2-en-VPA exerted anticonvulsant effects against kindled seizures only at doses which were associated with motor impairment" 09/01/1991 - "In most seizure models, trans-2-en-VPA was more potent than valproate, when both compounds were compared at their individual times of peak effect" Order ALL the reference details at left...
2.	Epilepsy (Aura) 03/23/1984 - "The anticonvulsant potency of 2-propyl-2-pentenoic acid (2-en-VPA; trans isomer), a major metabolite of the antiepileptic valproic acid (VPA), was evaluated in different animal models of epilepsy and compared with the respective data for VPA" Order ALL the reference details at left...
3.	Ataxia (Dyssynergia) 09/01/1991 - "Similarly, in dogs trans-2-en-VPA exerted anticonvulsant effects at doses below those which induced sedation and ataxia" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Valproic Acid (Valproate, Semisodium)

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