|1.||Ayuko, Washington O: 1 article (09/2004)|
|2.||Singh, Harjit: 1 article (09/2004)|
|3.||Dunn, Simon: 1 article (09/2004)|
|4.||Kinchington, Derek: 1 article (09/2004)|
|5.||Lattmann, Eric: 1 article (09/2004)|
|6.||Tisdale, Michael J: 1 article (09/2004)|
|1.||Aberrant Crypt Foci
08/01/1999 - "In order to study this experimentally, we have examined the effects of 3,4-dichloro-5-hydroxy-2[5H]-furanone (mucochloric acid, MCA) and 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX), mutagenic and genotoxic compounds in drinking water, on aberrant crypt foci and tumours in the intestines of male F344 rats and Balb/cA mice, and C57BL/6J-Min (multiple intestinal neoplasia)/+ mice of both sexes, in six independent experiments. "
09/01/2004 - "The pseudo acid chloride 3 was reacted further into the bis aziridine 8. Reduction of the mucochloric acid 1a furnished the trichlorofuranone 3. The cytotoxicity of these simple and bis-cyclic butenolides have been evaluated in tissue culture on MAC13 and MAC16 cancer cell lines using the MTT cytotoxicity assay. "