4-methylumbelliferyl glucoside

RN given refers to (beta)-isomer

Also Known As:

4-MU-alpha-glucoside; 4-MU-glucoside; 4-methylumbelliferyl glucoside, (alpha)-isomer; 4-methylumbelliferyl-alpha-D-glucopyranoside; 4-methylumbelliferyl-beta-D-glucopyranoside; MUbetaGlu

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Glucosides: 639
    - 4-methylumbelliferyl glucoside: 7
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        Umbelliferones: 3
        Hymecromone: 123
        4-methylumbelliferyl glucoside: 7
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        Umbelliferones: 3
        Hymecromone: 123
        4-methylumbelliferyl glucoside: 7

Related Diseases

1.	Glycogen Storage Disease Type II (Pompe's Disease) 06/01/1978 - "Pompe's disease: diagnosis in kidney and leucocytes using 4-methylumbelliferyl-alpha-D-glucopyranoside." 07/15/1977 - "Diagnosis of Pompe's disease in cultured skin fibroblasts and primary amniotic fluid cells using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate." 07/15/1977 - "The possible interference of neutral alpha-D-glucosidase in the diagnosis of Pompe's disease using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate for the assay of acid alpha-D-glucosidase was investigated. " 03/01/1978 - "Fibroblasts from patients with the adult, juvenile, and infantile form of glycogenosis type II (Pompe disease) were cultured under standardized conditions, and the activity of acid alpha-glucosidase (E.C.3.2.1.20) towards glycogen, maltose, and 4-methylumbelliferyl-alpha-D-glucopyranoside was measured. " 01/01/1978 - "Isoelectric precipitation at pH 5.0 and the use of the inhibitors, turanose, maltose and citrate, enabled the diagnosis of Pompe's disease to be made in dextran-isolated leucocytes using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate. "
2.	Gaucher Disease (Gaucher's Disease) 01/01/1990 - "We examined the property of beta-D-glucosidase in normal child liver, spleen and brain tissues and in tissues affected by Gaucher disease using two different kinds of synthetic substrates, 2-hexadecanoylamino-4-nitrophenyl-beta-D-glucopyranoside (HN Glc) and 4-methylumbelliferyl-beta-D-glucopyranoside (MU Glc). " 09/01/1982 - "The beta-glucosidase activity, as measured with 4-methylumbelliferyl-beta-D-glucopyranoside as the substrate, in the homogenates of brain from four cases of Gaucher's disease was less sensitive to inhibition by conduritol B epoxide (CBE) when compared with normal brain beta-glucosidase. " 09/25/1980 - "To date, enzymatic diagnosis of Gaucher's disease via a fluorometric assay procedure which utilizes 4-methylumbelliferyl-beta-D-glucopyranoside as a substrate has not been possible when liver serves as the source of enzyme since currently employed fluorometric procedures cannot adequately differentiate between a broad-specificity beta-glucosidase and lysosomal glucocerebrosidase activities in crude extracts of liver. "

Related Drugs and Biologics

1.	Maltose
2.	Glucosidases
3.	beta-Glucosidase
4.	Acids
5.	Complex Mixtures
6.	Citric Acid (Citrate)
7.	Glycogen
8.	Glucosylceramidase (Glucocerebrosidase)
9.	Enzymes
10.	Dextrans (Dextran)