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dioctyl adipate (DEHA)

Also Known As:
DEHA; DEHA compound; adipic acid, dioctyl ester; di-2-ethyl-hexyl adipate; diethylhexyl adipate; diethylhexyladipate; di-2-ethylhexyl adipate
Networked: 20 relevant articles (0 outcomes, 5 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Abd El-Rahman, Ghada I: 1 article (01/2021)
2. Abd-Elhakim, Yasmina M: 1 article (01/2021)
3. Aly, Sanaa S H: 1 article (01/2021)
4. Behairy, Amany: 1 article (01/2021)
5. Fahmy, Esraa M: 1 article (01/2021)
6. Brüning, Thomas: 1 article (03/2020)
7. Bury, Daniel: 1 article (03/2020)
8. Kling, Hans-Willi: 1 article (03/2020)
9. Koch, Holger M: 1 article (03/2020)
10. Nehring, Alexandra: 1 article (03/2020)

Related Diseases

1. Body Weight (Weight, Body)
03/01/2003 - "A dose-range finding study followed by a dose-response/effect study in Wistar rats investigated whether pre- and postnatal DEHA doses of 0, 800, or 1200mg/kg/day body weight and doses of 0, 200, 400, or 800mg/kg/day (main study) elicited developmental toxicity including antiandrogenic effects. "
03/01/2003 - "DEHA also induced a permanent decrease in offspring body weight (800mg/kg/day). "
06/01/2019 - "At the high-dose, DEHA-related findings included clinical observations, decreased body weight gain and food consumption, increased liver weight in females associated with minimal hepatocellular hypertrophy, and decreased thymus weight in males and females without histopathology findings. "
05/01/1996 - "The major effects of chronic dosing were mortality in female rats at 500 mg/kg and in male and female mice at 750 mg/kg, accompanied by reductions in body weight gain in rats at 150 and 500 mg/kg and in mice at 750 mg/kg. Direct comparison of any tumorogenic effects of 2EH given alone to female mice with those due to 2EH formed in vivo from DEHA, DEHP, or TEHP is limited by the high mortality caused by 2ER in female mice at equivalent doses of 2EH. "
03/01/1995 - "Based on statistics on dietary habits it is concluded that the retail packaging of small portions of cheese even in a 'low migration' PVC cling film may lead to consumer intakes of DEHA close to or above the tolerable daily intake of 0.3 mg/kg body weight as defined by the EEC Scientific Committee for Food. "
2. Neoplasms (Cancer)
3. Follicular Cyst (Follicular Cysts)
4. Anemia
5. Carcinogenesis

Related Drugs and Biologics

1. adipic acid (adipate)
2. Solutions
3. Dimethyl Sulfoxide (DMSO)
4. Corn Oil (Oil, Corn)
5. 4-bromobenzoyl-(alpha-aminoisobutyric acid)(5)-leucyl-(alpha-aminoisobutyric acid)(2)-methoxy (BALA)
6. Diethylhexyl Phthalate (DEHP)
7. DNA (Deoxyribonucleic Acid)
8. Dehydroepiandrosterone (DHEA)
9. Thioacetamide (Thioacetamid)
10. Polyvinyl Chloride (PVC)