|1.||Thornalley, Paul J: 4 articles (05/2011 - 08/2003)|
|2.||Ramana, Kota V: 3 articles (01/2012 - 05/2009)|
|3.||Zeier, Martin: 2 articles (01/2015 - 05/2011)|
|4.||Müller-Krebs, Sandra: 2 articles (01/2015 - 05/2011)|
|5.||Schwenger, Vedat: 2 articles (01/2015 - 05/2011)|
|6.||Nagai, Ryoji: 2 articles (02/2014 - 04/2012)|
|7.||Tschoepe, Diethelm: 2 articles (09/2013 - 09/2006)|
|8.||Stirban, Alin: 2 articles (09/2013 - 09/2006)|
|9.||Navis, Gerjan J: 2 articles (01/2012 - 07/2010)|
|10.||Bakker, Stephan J L: 2 articles (01/2012 - 07/2010)|
|1.||Diabetic Neuropathies (Diabetic Neuropathy)
06/01/2010 - "The anti-AGE property of benfotiamine certainly makes it effective for the treatment of diabetic neuropathy, nephropathy and retinopathy. "
01/13/2006 - "Benfotiamine has shown therapeutic efficacy in the treatment of painful diabetic neuropathy in human beings. "
01/01/1997 - "The therapeutic efficacy of Milgamma was greater in patients with early-stage diabetes as compared with those with advanced diabetic neuropathy. "
01/01/1997 - "Therapeutic efficacy of "Milgamma" in patients with painful diabetic neuropathy."
11/01/2008 - "Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study."
05/01/2012 - "Our findings suggest that high-dose benfotiamine (300 mg/day) supplementation over 24 months has no significant effects upon peripheral nerve function or soluble markers of inflammation in patients with type 1 diabetes."
01/01/2012 - "Compared to placebo, benfotiamine did not result in significant reductions in plasma or urinary AGEs or plasma markers of endothelial dysfunction and low-grade inflammation. "
05/15/2010 - "Thus, our results elucidate the molecular mechanism of the anti-inflammatory action of benfotiamine in LPS-induced inflammation in murine macrophages. "
05/01/2009 - "Therefore, benfotiamine could be used as a novel therapeutic agent for the treatment of ocular inflammation, especially uveitis."
01/01/2012 - "Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy."
01/01/1997 - "Therapeutic efficacy was assessed on the basis of within-patient differences in pain severity between Milgamma and Neurobex-treated patients and in vibration perception thresholds using the Rydel-Seiffer biothesiometer at baseline and at the end of the study. "
01/01/2009 - "An open controlled study of efficacy of the vitamin B complex (milgamma) has been performed in 38 patients with vertebrogenic lumbosacral radiculopathy suffered from moderate or severe pain during 1 month or longer. "
01/01/2009 - "Using of milgamma in combination with NSAIDS leads to the rapid and long-standing regress of pain syndrome in patients with lumbosacral radiculopathy."
01/01/2008 - "In the comparison of vitamin B with placebo, two small trials showed no significant short-term benefit in pain intensity while one of the trials showed a small significant benefit in vibration detection from oral benfotiamine, a derivative of thiamine. "
01/01/2009 - "In an attempt to provide more direct evidence concerning the possible antinociceptive effect of resveratrol-benfotiamine combination on neurogenic pain, we investigated whether resveratrol and benfotiamine administered alone or in combination decrease capsaicin induced nociception in mice. "
|4.||Neuralgia (Stump Neuralgia)
01/01/1997 - "Statistically significant relief of both background and peak neuropathic pain was achieved in all of the Milgamma-treated patients and vibration perception thresholds dramatically improved with a median of 1.56 measured on the biothesiometer scale (t = 3.24, P < 0.01). "
01/13/2006 - "The purpose of this study was to assess the possible antinociceptive and antiallodynic effect of benfotiamine in inflammatory and neuropathic pain models in the rat. "
03/01/2014 - "Finally, we suppose that oral benfotiamine replacement therapy may be useful to ameliorate analgesic effect of mu-opioid agonists on neuropathic pain in diabetic case."
01/13/2006 - "Benfotiamine relieves inflammatory and neuropathic pain in rats."
01/13/2006 - "Results indicate that oral administration of benfotiamine is able to reduce tactile allodynia from different origin in the rat and they suggest the use of this drug to reduce inflammatory and neuropathic pain in humans."
|5.||Peripheral Nervous System Diseases (PNS Diseases)
01/01/2008 - "One small trial in alcoholic peripheral neuropathy reported slightly greater improvement in vibration perception threshold with oral benfotiamine for eight weeks than placebo. "
07/01/2013 - "Benfotiamine diminishes peripheral neuropathy in diabetic humans and animals. "
07/01/2008 - "This effect of benfotiamine may be involved in the improvement of diabetic late complications, including peripheral neuropathy."
|3.||Vitamin B Complex (B Vitamins)
|9.||NF-kappa B (NF-kB)
|4.||Drug Therapy (Chemotherapy)