sucrose polyester (olestra)

11/01/1997 - "A randomized, double-blind study of the effect of olestra on disease activity in patients with quiescent inflammatory bowel disease. "
11/01/1997 - "To determine the effects of olestra, a zero-calorie fat substitute that is neither digested nor absorbed, on the well-being and disease state of persons with chronic inflammatory bowel disease (IBD) in remission. "
10/01/1997 - "Olestra and triglyceride ingestion resulted in a similar frequency of symptoms in normal adults and children and in people with chronic inflammatory bowel disease in remission. "
10/01/1997 - "The poligeenan-treated animals displayed mucosal damage similar to that seen in human inflammatory bowel diseases; therefore, these results suggest that patients with inflammatory bowel conditions will not absorb olestra to any greater extent than normal healthy people."

06/01/2002 - "In Study One fat substitution by Olestra resulted in a significant 1.7 kg weight loss from baseline. "
02/01/2002 - "Other studies are underway to examine the usefulness of olestra in long-term weight maintenance following weight loss. "
06/01/2005 - "After inclusion of olestra in his diet for 2 years, weight loss was successful without aggravation of his symptoms, and the patient reverted to normoglycemia and normolipidemia. "
02/01/2002 - "Because olestra provides no energy, it has the potential to be a useful tool in weight loss and weight maintenance. "
10/01/2003 - "Consumption of a low-fat diet containing olestra for 9 months produced significant improvement in cardiovascular risk factors, an effect largely explained by weight loss. "

06/01/2002 - "In Study Two, change in body weight and body fat from baseline were statistically significant in all groups, but the group with Olestra lost significantly more weight from baseline (-5.0 kg) than the other two groups. "
08/01/2011 - "However, rats previously exposed to both the high- and low-calorie chips exhibited increased body weight gain, food intake and adiposity when they were subsequently provided with a high fat, high calorie chow diet suggesting that experience with the chips containing olestra affected the ability to predict high calories based on the sensory properties of fat. "
08/01/2011 - "Food intake, body weight gain and adiposity were greater for rats that consumed both the high-calorie chips and the low-calorie chips with olestra compared to rats that consumed consuming only the high-calorie chips, but only if animals were also consuming a chow diet that was high in fat and calories. "
02/01/2002 - "A role for olestra in body weight management."
07/01/2001 - "The longer term effects of olestra on body weight requires further investigation. "

02/15/2000 - "Positive results on tests for steatorrhea in persons consuming olestra potato chips."
02/15/2000 - "Consumption of olestra can cause false-positive results on tests for steatorrhea and may therefore lead to an erroneous diagnosis of the malabsorption syndrome."
02/15/2000 - "When participants consumed 40 g of olestra per day, the excretion of fecal fat increased to levels observed in patients with steatorrhea caused by the malabsorption syndrome. "

02/15/2000 - "Consumption of olestra can cause false-positive results on tests for steatorrhea and may therefore lead to an erroneous diagnosis of the malabsorption syndrome."
02/15/2000 - "When participants consumed 40 g of olestra per day, the excretion of fecal fat increased to levels observed in patients with steatorrhea caused by the malabsorption syndrome. "