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Description: RN given refers to parent cpd; structure
Also Known As:| 1. | Pulmonary Heart Disease (Cor Pulmonale)
04/15/1977
- "Hypertrophy of pulmonary arteries and arterioles with cor pulmonale in rats induced by seneciphylline, a pyrrolizidine alkaloid."
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| 2. | Neoplasms (Cancer)
01/01/2008
- "Among the PAs definitively identified, senecionine, seneciphylline, and senkirkine are known tumorigens capable of inducing liver tumors in experimental animals, while seneciphylline N-oxide and senecionine N-oxide are probably tumorigenic due to their potential conversion into seneciphylline and senecionine via metabolic reduction in the body"
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| 3. | Hypertrophy
04/15/1977
- "Hypertrophy of pulmonary arteries and arterioles with cor pulmonale in rats induced by seneciphylline, a pyrrolizidine alkaloid."
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| 1. | p-Aminosalicylic Acid (PAS)
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| 2. | senecionine N-oxide
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| 3. | senkirkine
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| 4. | senecionine (integerrimine)
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