riddelliine

Subscribe to Selected New Research on riddelliine

20 relevant articles (0 outcomes, 7 trials/studies) found for this Bio-Agent

Description: structure

Also Known As:

13,19-didehydro-12,18-dihydroxysenecionan-11,16-dione

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

Alkaloids: 633

Pyrrolizidine Alkaloids: 61

riddelliine: 20

2-Ring Heterocyclic Compounds

Pyrrolizidine Alkaloids: 61

riddelliine: 20

Experts

1.	Moyer, C: 1 article (07/2004)
2.	Nyska, A: 1 article (07/2004)
3.	Maronpot, R R: 1 article (07/2004)
4.	Allen, D: 1 article (07/2004)
5.	Basabe, A: 1 article (07/2004)
6.	Chou, Ming W: 1 article (04/2004)
7.	Chan, Po-Cheun: 1 article (04/2004)
8.	Nichols, Jasyl: 1 article (04/2004)
9.	Fu, Peter P: 1 article (04/2004)
10.	Yan, Jian: 1 article (04/2004)

Related Diseases

1.	Hemangiosarcoma (Angiosarcoma) 08/01/2004 - "In recent studies, riddelliine, a pyrrolizidine alkaloid, was found to increase rates of replication and apoptosis and induce hemangiosarcoma in the liver of rats and mice" 05/01/2003 - "CONCLUSIONS: Under the conditions of these studies, there was clear evidence of carcinogenic activity of riddelliine in male and female F344/N rats based primarily on increased incidences of hemangiosarcoma in the liver" 11/01/2002 - "In National Toxicology Program 2-year studies, riddelliine induced high incidences of hemangiosarcoma in the liver of F344/N rats (both sexes) and B6C3F1 mice (males)" 11/25/2004 - "Riddelliine is a naturally occurring pyrrolizidine alkaloid that induces liver hemangiosarcomas in rats and mice" 08/01/2004 - "That estimated replication rates were found to be significantly higher for endothelial cells supports the supposition of induction of hemangiosarcoma by riddelliine in the liver." Get all the results and reference details, order at left...
2.	Neoplasms (Cancer) 09/01/2003 - "Riddelliine is a naturally occurring carcinogenic pyrrolizidine alkaloid that produces liver tumors in experimental animals" 05/01/2003 - "Decreased incidences of hepatocellular neoplasms in male and female mice were related to riddelliine administration." 01/01/2003 - "These results strongly indicate the mechanistic data on liver tumor induction obtained for riddelliine in laboratory rodents is highly relevant to humans." 01/01/2003 - "Riddelliine, a widespread naturally occurring genotoxic pyrrolizidine alkaloid, induced liver tumors in rats and mice in an NTP 2-year carcinogenicity bioassay" 07/15/2002 - "A recently completed 2-year bioassay of riddelliine carcinogenicity showed that male and female rats and male mice, but not female mice, developed liver tumors" Get all the results and reference details, order at left...
3.	Body Weight (Weight, Body) 01/01/2007 - "The female rats were gavaged with riddelliine at a dose of 1 mg/kg body weight 5 days a week for 12 weeks" 01/01/2007 - "RESULTS: Groups of 6 Big Blue Fisher 344 rats were treated with riddelliine at 1 mg/kg body weight by gavage five times a week for 12 weeks or fed a diet containing 8% comfrey root for 12 weeks" 11/25/2004 - "Female transgenic Big Blue rats were treated by gavage with 0.3 mg riddelliine per kg body weight, 5 days a week for 12 weeks" 06/01/2004 - "To examine the mutagenicity of riddelliine, groups of six female transgenic Big Blue rats were gavaged with 0.1, 0.3, and 1.0 mg riddelliine per kg body weight" 05/01/2003 - "2-YEAR STUDY IN RATS: Groups of 50 male and 50 female rats were administered 0 or 1 mg riddelliine/kg body weight in sodium phosphate buffer by gavage 5 days per week; additional groups of 50 female rats received 0.01, 0.033, 0.1, or 0.33 mg/kg. A wide dose range was used in female rats to better characterize the dose-response curve" Get all the results and reference details, order at left...
4.	Poisoning 05/01/2000 - "Tissue samples from pigs fed various amounts of the PA alkaloid riddelliine (from Senecio riddellii) were analyzed for pyrrolic metabolites, and the results were applied to the calibration curve to provide a measure of the degree of PA poisoning" Get all the results and reference details, order at left...
4 Diseases and 20 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	DNA Adducts
2.	retronecine
3.	dehydroretronecine
4.	Monocrotaline
5.	Pyrrolizidine Alkaloids
6.	Codon (Codons)
7.	otonecine
8.	2-nitrotoluene
9.	clivorine
10.	sodium phosphate (trisodium phosphate)
15 Drugs and Important Bio-Agents and 12 more articles analyzed in the Research Interface, order at left...

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License details >>

Price:

$490.00 access via web interface, 1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m", 1 year subscription

Proceed to Checkout >>