|1.||Hjelstuen, M H: 1 article (06/2007)|
|2.||Håberg, A: 1 article (06/2007)|
|3.||Sonnewald, U: 1 article (06/2007)|
|4.||Qu, H: 1 article (06/2007)|
|5.||Gauthier, Cindy: 1 article (03/2007)|
|6.||Comte, Blandine: 1 article (03/2007)|
|7.||Ntimbane, Thierry: 1 article (03/2007)|
|8.||Cambonie, Gilles: 1 article (03/2007)|
|9.||Abran, Daniel: 1 article (03/2007)|
|10.||Lavoie, Jean-Claude: 1 article (03/2007)|
|1.||Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/04/1994 - "The aim of this study was to evaluate the effect of 21-aminosteroid lipid peroxidation inhibitor, U74006F, on ischaemic brain tissue damage using the rat middle cerebral artery occlusion model. "
01/04/1994 - "Effect of 21-aminosteroid lipid peroxidation inhibitor, U74006F, in the rat middle cerebral artery occlusion model."
06/01/2007 - "The aim of the present study was to assess the effect of post ictal administration of the pyrrolopyrimidine lipid peroxidation inhibitor, U-101033E, on infarct volume and neuronal and astrocytic metabolism in rats with transient middle cerebral artery occlusion (MCAO). "
06/01/2007 - "Effect of the pyrrolopyrimidine lipid peroxidation inhibitor U-101033E on neuronal and astrocytic metabolism and infarct volume in rats with transient middle cerebral artery occlusion."
02/01/1996 - "The purpose of the present investigation was to determine if post-ischemic treatment with the 21-aminosteroid lipid peroxidation inhibitor tirilazad mesylate (U-74006F) could affect reperfusion brain edema during the first 3h following a 3h period of middle cerebral artery occlusion-induced focal ischemia in cynomolgus monkeys. "
06/01/1998 - "The lipid peroxidation inhibitor H290/51 attenuated cardiac injury induced by ischemia-reperfusion."
06/01/1995 - "Beneficial effects of H290/51, a new lipid peroxidation inhibitor, on functional recovery after ischemia and reperfusion in isolated cold-arrested rat hearts."
06/01/1995 - "In the present study, a newly synthetized lipid peroxidation inhibitor H290/51 [cis-7methyl-9-methoxy-5,5a,b,10b- tetrahydroindeno(2,1-6 indole)] was evaluated for its effects on myocardial functional recovery during reperfusion after 30-min global ischemia in isolated cold-arrested rat hearts. "
03/15/1998 - "The lipid peroxidation inhibitor indenoindole H290/51 protects myocardium at risk of injury induced by ischemia-reperfusion."
10/03/1994 - "Effects of the lipid peroxidation inhibitor tirilazad mesylate (U-74006F) on gerbil brain eicosanoid levels following ischemia and reperfusion."
|3.||Brain Ischemia (Cerebral Ischemia)
06/01/1998 - "Postischemic application of lipid peroxidation inhibitor U-101033E reduces neuronal damage after global cerebral ischemia in rats."
09/01/1996 - "Tirilazad mesylate, a nonglucocorticoid 21-aminosteroid lipid peroxidation inhibitor, has shown promise as a neuroprotectant in experimental models of focal cerebral ischemia. "
08/01/1988 - "21-Aminosteroid lipid peroxidation inhibitor U74006F protects against cerebral ischemia in gerbils."
06/01/1992 - "We examined the cytoprotective effect of the lipid peroxidation inhibitor tirilazad mesylate (U74006F) in rodent models of neocortical infarction induced by transient and permanent focal cerebral ischemia. "
09/01/2000 - "This study investigates the effects of acamprosate, a glutamatergic modulator, and the lipid peroxidation inhibitor U-101033E on neurological outcome following incomplete cerebral ischemia and reperfusion in rats. "
|4.||Acute Kidney Injury (Acute Renal Failure)
10/01/1995 - "The present study examined directly in renal proximal tubular (LLC-PK1) cells whether hydrogen peroxide, a reactive oxygen species implicated in many models of acute renal injury, induces F2-isoprostane production and whether its production can be inhibited by the recently synthesized lipid peroxidation inhibitor 21-aminosteroid (lazaroid U-74389G). "
05/01/1996 - "The purpose of this study was to investigate the role of oxygen radical-induced lipid peroxidative mechanisms in trophic deprivation-induced apoptotic motor neuronal degeneration by testing the ability of the 21-aminosteroid lipid peroxidation inhibitor tirilazad mesylate (U-74006F) to attenuate the retrograde degeneration of facial motor neurons following axotomy in 14-day-old rat pups. "
|2.||U 101033E (U-101033E)
|3.||F2-Isoprostanes (F2 Isoprostanes)
|4.||Reactive Oxygen Species (Oxygen Radicals)
|6.||Hydrogen Peroxide (Hydroperoxide)